3-Chlorpropyltrimethoxysilan

Liquid

Liquid; [Reference #1] Colorless liquid; [Alfa Aesar MSDS]

This chemical does not meet GHS hazard criteria for 83.4% (181 of 217) of all reports.

Warning

H226 (11.5%): Flammable liquid and vapor [Warning Flammable liquids]

P210, P233, P240, P241, P242, P243, P280, P303+P361+P353, P370+P378, P403+P235, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 217 reports by companies from 8 notifications to the ECHA C&L Inventory.；Reported as not meeting GHS hazard criteria per 181 of 217 reports by companies.；There are 5 notifications provided by 36 of 217 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Chemical: Silane, (3-chloropropyl)trimethoxy-

Silane, (3-chloropropyl)trimethoxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Silane, (3-chloropropyl)trimethoxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 03-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/16008；Status: Active Update: 21-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/33821

3-(Chloropropyl)-trimethoxysilane: Does not have an individual approval but may be used under an appropriate group standard

Rapidly hydrolyzed producing 3 moles of methanol for every mole of silanetriol; Methanol is expected to cause any toxicity observed; Not a skin sensitizer in guinea pigs; A repeated-dose inhalation study produced no adverse effects at concentrations up to 100 ppm; Clinical observations in a micronucleus assay of mice include ataxia, tremors, prostration, myoclonic jerks, and vocalization; No reproductive or developmental toxicity observed in an inhalation study of rats at concentrations up to 100 ppm; [Reference #1] Reacts with water evolving methanol; A skin and strong eye irritant; [Alfa Aesar MSDS] See Methyl alcohol. See Trimethoxypropylsilane.

Flam. Liq. 3 (11.5%)

Flammable liquids - Category 3；Skin corrosion/irritation - Category 2；Serious eye damage/eye irritation - Category 2B；Specific target organ toxicity - Single exposure - Category 3 (Narcotic effects)；Specific target organ toxicity - Repeated exposure - Category 2 (urinary bladder)

20 [mg/m3]

220 [mg/m3]

1300 [mg/m3]

Chemical: Silane, (3-chloropropyl)trimethoxy-

Silane, (3-chloropropyl)trimethoxy- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Silane, (3-chloropropyl)trimethoxy- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 03-05-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/16008；Status: Active Update: 21-06-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/33821

3-(Chloropropyl)-trimethoxysilane: Does not have an individual approval but may be used under an appropriate group standard

All Other Basic Inorganic Chemical Manufacturing；Synthetic Rubber Manufacturing；All Other Chemical Product and Preparation Manufacturing；Paint and Coating Manufacturing；All Other Basic Organic Chemical Manufacturing

Silane, (3-chloropropyl)trimethoxy-: ACTIVE