Pentaethylene glycol

Liquid

Liquid; [OECD SIDS - Pentaethylene Glycol] Colorless liquid; [Alfa Aesar MSDS]

150.1 Ų [M+Na]+ [CCS Type: DT; Buffer gas: N2; Ionization: ESI+; Dataset: TOXCAST; Source Identifier: DTXSID4027579]

149.58 Ų [M+Na]+ [CCS Type: TW; Method: calibrated with polyalanine and drug standards]

Warning

H315 (97.3%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 146 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Chemical: 3,6,9,12-Tetraoxatetradecane-1,14-diol

Chemical: Amylopectin, phosphate, 2-hydroxypropyl ether

3,6,9,12-Tetraoxatetradecane-1,14-diol is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 3,6,9,12-Tetraoxatetradecane-1,14-diol are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

FRI - indicates a polymeric substance containing no free-radical initiator in its Inventory name but is considered to cover the designated polymer made with any free-radical initiator regardless of the amount used.

Amylopectin, phosphate, 2-hydroxypropyl ether: Does not have an individual approval but may be used under an appropriate group standard

3,6,9,12-Tetraoxatetradecane-1,14-diol: Does not have an individual approval but may be used under an appropriate group standard

IMAP assessments - Amylopectin, phosphate, 2-hydroxypropyl ether: Human health tier I assessment

IMAP assessments - 3,6,9,12-Tetraoxatetradecane-1,14-diol: Human health tier I assessment

Causes liver and male reproductive effects in 26-week intermittent oral studies of rats; [RTECS] Ethylene glycols: Category members demonstrate decreasing potential for systemic, reproductive, and developmental toxicity as the molecular weight increases; low dermal bioavailability; no evidence of skin sensitization in humans or guinea pigs; some evidence of mutagenicity; and no evidence of carcinogenicity. Pentaethylene glycol has the highest molecular weight in the category. The lowest molecular weight members produce renal toxicity by repeated oral exposure and developmental toxicity when rapidly ingested (bolus). These effects are not expected to occur with pentaethylene glycol; [OECD SIDS - Ethylene Glycols Category] A strong eye irritant; [Alfa Aesar MSDS]

Used in commercial mixtures (with tri- and tetraethylene glycols) added to brake fluids and in cement grinding; [OECD SIDS - Pentaethylene Glycol] Not manufactured in the pure form in the US; Commercial mixtures with tetraethylene glycol are produced as byproducts following distillation of ethylene, diethylene, and triethylene glycols; [OECD SIDS - Ethylene Glycols Category]

Cement Producing [Category: Industry]

EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives

Safer Chemical Classes -> Green half-circle - The chemical is expected to be of low concern

All Other Chemical Product and Preparation Manufacturing

3,6,9,12-Tetraoxatetradecane-1,14-diol: ACTIVE

Amylopectin, phosphate, 2-hydroxypropyl ether: ACTIVE