N'-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxysuccinamidmonohydrochlorid

Deferoxamine Hydrochloride

HCID 62880
NotizenReaktionen
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

CAS
1950-39-6
Standard-SMILES
CC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN.Cl
InChIKey
KCRQZLMAZHZDCL-UHFFFAOYSA-N
Summenformel
C25H49ClN6O8
Durchschnittliche Molmasse
597,1 g/mol
Monoisotopische Masse
596,3300402

Überblick

Deferoxamine Hydrochloride is the hydrochloride salt form of deferoxamine, an iron chelating agent. Deferoxamine chelates iron from intra-lysosomal ferritin and hemosiderin forming ferrioxamine, a water-soluble chelate excreted by the kidneys and in the feces via the bile. This agent does not readily bind iron from transferrin, hemoglobin, myoglobin or cytochrome. (NCI)

Namen und Bezeichner

Bevorzugter Name
Deferoxamine Hydrochloride
IUPAC
N-[5-[[4-[5-[acetyl(hydroxy)amino]pentylamino]-4-oxobutanoyl]-hydroxyamino]pentyl]-N'-(5-aminopentyl)-N'-hydroxybutanediamide;hydrochloride
Lokaler Name
N'-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxysuccinamidmonohydrochlorid
Englischer Name
N'-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxysuccinamide monohydrochloride
Summenformel
C25H49ClN6O8
Molmasse
597.14496

Namen und Synonyme

Deferoxamine hydrochlorideDeferoxamine HCl1950-39-6Deferoxamine hydrochloride [USAN]Ba-29837G9VYJ96FOJDesferrioxamine hydrochlorideEINECS 217-767-4Ba 29837NSC-268993DTXSID50173157Deferoxamine hydrochloride (USAN)
Weitere Namen anzeigen
Butanediamide,N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxy-,hydrochloride (1:1)
DEFEROXAMINE HYDROCHLORIDE [MI]NSC 268993DEFEROXAMINE HYDROCHLORIDE [WHO-DD]NSC268993N'-(5-((4-((5-(Acetylhydroxyamino)pentyl)amino)-1,4-dioxobutyl)hydroxyamino)pentyl)-N-(5-aminopentyl)-N-hydroxysuccinamide monohydrochlorideN'-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxysuccinamide monohydrochlorideN-(5-{3-((5-Aminopentyl)hydroxycarbamoyl)propionamido}pentyl)-3-{(5-(N-hydroxyacetamido)pentyl)carbamoyl}propionohydroxamic acid monohydrochlorideN-(5-(3-((5-AMINOPENTYL)HYDROXYCARBAMOYL)PROPIONAMIDO)PENTYL)-3-((5-(N-HYDROXYACETAMIDO)PENTYL)CARBAMOYL)PROPIONOHYDROXAMIC ACID MONOHYDROCHLORIDE

Datenbank-Bezeichner

CAS
1950-39-6
PubChem CID
62880
DTXSID
DTXSID50173157
ChEMBL
CHEMBL2002581
UNII
G9VYJ96FOJ
EC Number
217-767-4

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
206 Ų
H-Brücken-Donoren
7
H-Brücken-Akzeptoren
9
Frei drehbare Bindungen
23
Schwere Atome
40

Physikochemische Eigenschaften

Schmelzpunkt
172 · 172-175°

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.

Danger

H315 (66.7%): Causes skin irritation [Warning Skin corrosion/irritation]

P233, P260, P261, P264, P264+P265, P271, P272, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 3 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory InformationREACH registered substance: N'-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxysuccinamide monohydrochloride (EC: 217-767-4)
Hazard Classes and CategoriesSkin Irrit. 2 (66.7%)

Sicherheitsdaten

Alarmwort
Achtung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H315

Chemie und Industrie

Anbieter3 Anbieter

陕西缔都医药化工有限公司029-029-81120477 17792793610 · [email protected]
北京泰和景明医药科技有限公司15011440205 · [email protected]
XIAMEN AMITY INDUSTRY AND TRADE CO., LTD.+8618950047208 · [email protected]

Zugehörige Reaktionen

1
Reaktionsaufzeichnung erstellen

Notizen zur Verbindung

Wird geladen…