Identifikatoren & physikalische Daten
| CAS No. | 96946-41-7 |
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| Summenformel | C53H72N2O12+2 |
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| Durchschnittliche Molmasse | 929,1 g/mol |
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| Monoisotopische Masse | 928,50852574 g/mol |
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| SMILES | COc1ccc(C[C@@H]2c3cc(OC)c(OC)cc3CC[N@+]2(C)CCC(=O)OCCCCCOC(=O)CC[N@@+]2(C)CCc3cc(OC)c(OC)cc3[C@H]2Cc2ccc(OC)c(OC)c2)cc1OC |
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| InChIKey | YXSLJKQTIDHPOT-LJCJQEJUSA-N |
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| PubChem CID | 62887 |
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| ChEMBL | CHEMBL1201248 |
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| ChEBI | CHEBI:140621 |
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| DTXSID | DTXSID60873212 |
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Chemische & physikalische Eigenschaften
| XLogP | 7,9 |
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| Polarare Oberfläche (TPSA) | 126 |
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| H-Brücken-Donoren | 0 |
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| H-Brücken-Akzeptoren | 12 |
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| Frei drehbare Bindungen | 26 |
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| Schwere Atome | 67 |
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| Formalladung | 2 |
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| Komplexität | 1.390 |
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| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
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| Human Drugs | Breast FeedingLactationMilk, HumanMuscle RelaxantsNeuromuscular Nondepolarizing Agents |
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Sicherheit & Vorschriften
| Unerwünschte Wirkungen | Adverse effects are uncommon with the use of cisatracurium. Adverse reactions occurred at a rate of less than 1% and included bradycardia, hypotension, bronchospasm, rash, anaphylaxis, prolonged neuromuscular blockade, and myopathy. |
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| Toxizitätsübersicht | Overdose with cisatracurium may result in neuromuscular blockade beyond the time needed for surgery and anesthesia. The primary treatment is maintaining sedation, a patent airway, and controlled ventilation until recovery of neuromuscular function is assured. There should be no attempt at reversal if there is evidence or suspicion of complete neuromuscular blockade. |
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| Effects During Pregnancy and Lactation | ◉ Summary of Use during Lactation |
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