Grundinformationen
- CAS
31002-79-6- Standard-SMILES
CC(CNC(=O)c1ccccc1)C(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C- InChIKey
GUYPYYARYIIWJZ-CYEPYHPTSA-N- Summenformel
- C35H42FNO8
- Durchschnittliche Molmasse
- 623,7 g/mol
- Monoisotopische Masse
- 623,28944546
Überblick
Triamcinolone benetonide is a corticosteroid hormone.
Namen und Bezeichner
- Bevorzugter Name
- Triamcinolone Benetonide
- IUPAC
- [2-[(1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] 3-benzamido-2-methylpropanoate
- Lokaler Name
- Triamcinolonbenetonid
- Englischer Name
- Triamcinolone benetonide
- Summenformel
- C35H42FNO8
- Molmasse
- 623.714
Namen und Synonyme
triamcinolone benetonide31002-79-6TibicortenTriamcinolona benetonidoTriamcinoloni benetonidum9DXL8A82MIDTXSID601026586RefChem:190832DTXCID401510743triamcinolone acetonide benzoyl-beta-aminoisobutyrate250-427-39-fluoro-11beta, 16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione Cyclic 16,17-acetal with Acetone 21-ester with n-benzoyl-2-methyl-beta-alanine
Weitere Namen anzeigen
Triamcinolon benetonideTriancinolone BenetonideTriamcinolone acetonide benzoyl-b-aminoisobutyrateTriamcinolone acetonide 21-(benzoyl-b-aminoisobutyrate)Triamcinolone Acetonide Impurity 22 (Triamcinolone Benetonide)9-Fluoro-11β-hydroxy-21-[1-oxo-2-methyl-3-(benzoylamino)propoxy]-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione9-Fluoro-11β,21-dihydroxy-16α,17-[isopropylidenebis(oxy)]pregna-1,4-diene-3,20-dione 21-(3-benzoylamino-2-methylpropanoate)
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 4,6
- Polarare Oberfläche (TPSA)
- 128 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 9
- Frei drehbare Bindungen
- 8
- Schwere Atome
- 45
- Formalladung
- 0
- Komplexität
- 1.340
Experimentelle und physikochemische Eigenschaften
DrugsPharmaceuticals -> Dermatologicals -> Corticosteroids, dermatological preparations
Physikochemische Eigenschaften
- Schmelzpunkt
- 203 · 203-207°
- Siedepunkt
- 782 · 782.0±60.0 °C(Predicted)
- Dichte
- 1.31 · 1.31±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- Soluble in DMSO
- pka
- 13.09 · 13.09±0.70(Predicted)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- Alarmwort
- Warnung
- Gefahrenhinweise
- Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H315
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
A group of CORTICOSTEROIDS that affect carbohydrate metabolism (GLUCONEOGENESIS, liver glycogen deposition, elevation of BLOOD SUGAR), inhibit ADRENOCORTICOTROPIC HORMONE secretion, and possess pronounced anti-inflammatory activity. They also play a role in fat and protein metabolism, maintenance of arterial blood pressure, alteration of the connective tissue response to injury, reduction in the number of circulating lymphocytes, and functioning of the central nervous system.
Anwendungen
VerwendenTriamcinolone Benetonide functions as a pharmaceutical inflammation inhibitor, or an antiinflammatory agent in animals.
Anbieter12 Anbieter
陕西缔都新材料有限公司81124267 17392282731 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
上海柯维化学技术有限公司021-64609169 18901607656 · [email protected]
陕西缔都医药化工有限公司+86-029-81138252 +86-173 9270 1263 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226 · [email protected]
上海乾平生物医药科技有限公司（宁波仓库发货）021-61537865 13585780846 · [email protected]
杭州洁汉化工有限公司
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