Ciprofloxacin Hydrochloride Anhydrous
Grundinformationen
- CAS
86483-48-9- Standard-SMILES
Cl.O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O- InChIKey
DIOIOSKKIYDRIQ-UHFFFAOYSA-N- Summenformel
- C17H19ClFN3O3
- Durchschnittliche Molmasse
- 367,8 g/mol
- Monoisotopische Masse
- 367,1098973
Überblick
Ciprofloxacin hydrochloride (anhydrous) is the anhydrous form of the monohydrochloride salt of ciprofloxacin. It has a role as an antiinfective agent, an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor and a topoisomerase IV inhibitor. It contains a ciprofloxacin.
Namen und Bezeichner
- Bevorzugter Name
- Ciprofloxacin Hydrochloride Anhydrous
- IUPAC
- 1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride
- Englischer Name
- Ciprofloxacin hydrochloride
- Summenformel
- C17H18FN3O3.xHCl
- Molmasse
- 367.81
Namen und Synonyme
93107-08-5Ciprofloxacin Hydrochloride Anhydrous0MP32MFP6CRefChem:91867286483-48-91-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid xhydrochlorideCiprofloxacin monohydrochloride1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid hydrochlorideCHEBI:310388Bay o 9867Ciprofloxacin (monohydrochloride)
Weitere Namen anzeigen
CIPROFLOXACIN HYDROCHLORIDE MONOHYDRATECiprofloxacin base/HCLCifloxCiprofloxacin Impurity 14CIPROFLOXACIN HCL HYDRATECIPROFLOXACIN HCL (ANHYDROUS)Enrofloxacin nicotinate USP/EP/BP
BAY-O-9867CiproxanCiproxinciprofloxacin hydrochloride (anhydrous)BAY-o 98671-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;hydrochloride1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)-1,4-dihydro-3-quinolinecarboxylic acid hydrochlorideciprofloxacine hydrochloride
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 72,9 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 7
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 25
- Formalladung
- 0
- Komplexität
- 571
Physikochemische Eigenschaften
- Schmelzpunkt
- 300 °C · >300 °C
- storage temp.
- Inert atmosphere,Room Temperature
- Löslichkeit
- DMSO (Slightly, Heated), Methanol (Slightly, Heated)
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- BCS Class
- 3 · 3/1
- InChI
- InChI=1S/C17H18FN3O3.ClH/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24;/h7-10,19H,1-6H2,(H,23,24);1H
- InChIKey
- DIOIOSKKIYDRIQ-UHFFFAOYSA-N
- SMILES
- O=C1C(=CN(C2CC2)C2=CC(N3CCNCC3)=C(F)C=C12)C(=O)O.Cl
- CAS Datenbank
- 86483 · 86483-48-9(CAS DataBase Reference)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H315 (33.3%): Causes skin irritation [Warning Skin corrosion/irritation]
P233, P260, P261, P264, P264+P265, P271, P272, P273, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P333+P317, P337+P317, P342+P316, P362+P364, P391, P403, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 3 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (33.3%)
Sicherheitsdaten
- hs_code
- 29419000
- risk_code
- 36/37/38
- hazard_code
- Xi
- safety_code
- 26-36
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Substances that inhibit the growth or reproduction of BACTERIA.
Compounds that inhibit the activity of DNA TOPOISOMERASE II. Included in this category are a variety of ANTINEOPLASTIC AGENTS which target the eukaryotic form of topoisomerase II and ANTIBACTERIAL AGENTS which target the prokaryotic form of topoisomerase II.
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 CYP1A2.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Ergänzende Hinweise
DefinitionChEBI: The anhydrous form of the monohydrochloride salt of ciprofloxacin.
Zugehörige Reaktionen
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