HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
tert-Butoxycarbonyl-D-leucine
BOC-D-LEU-OH · BOC-D-LEUCINE · (R)-2-((TERT-BUTOXYCARBONYL)AMINO)-4-METHYLPENTANOIC ACID · BOC-D-LEU · n-boc-d-leucine · N-(tert-Butoxycarbonyl)-D-leucine Hydrate · BOC-D-LeuClne · BOC-D-LEU-OH2O
Identifikatoren & physikalische Daten
| CAS No. | 16937-99-8 |
|---|---|
| Summenformel | C11H21NO4 |
| Durchschnittliche Molmasse | 231,29 g/mol |
| Monoisotopische Masse | 231,14705815 g/mol |
| SMILES | CC(C)C[C@@H](NC(=O)OC(C)(C)C)C(=O)O |
| InChIKey | MDXGYYOJGPFFJL-MRVPVSSYSA-N |
| PubChem CID | 637604 |
| ChEMBL | CHEMBL1222066 |
| EC No. | 834-861-6 |
| DTXSID | DTXSID501308165 |
Chemische & physikalische Eigenschaften
| XLogP | 2,2 |
|---|---|
| Polarare Oberfläche (TPSA) | 75,6 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 6 |
| Schwere Atome | 16 |
| Formalladung | 0 |
| Komplexität | 255 |
| Schmelzpunkt | 85-87 °C(lit.) |
| Siedepunkt | 356.0±25.0 °C(Predicted) |
| Dichte | 1.061±0.06 g/cm3(Predicted) |
| Brechungsindex | 25 ° (C=2, AcOH) |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Room Temperature |
| Löslichkeit | Acetic Acid (Sparingly), DMSO (Slightly), Methanol (Slightly) |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 4.02±0.21(Predicted) |
| Farbe | White |
| BRN | 2331060 |
| Hauptanwendungen | peptide synthesis |
| InChI | InChI=1S/C11H21NO4/c1-7(2)6-8(9(13)14)12-10(15)16-11(3,4)5/h7-8H,6H2,1-5H3,(H,12,15)(H,13,14)/t8-/m1/s1 |
| InChIKey | MDXGYYOJGPFFJL-MRVPVSSYSA-N |
| SMILES | C(O)(=O)[C@@H](CC(C)C)NC(OC(C)(C)C)=O |
| CAS Datenbank | 16937-99-8(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.WarningH315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (50%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29241990 |
| Sicherheitshinweise (S) | 24/25 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
N-Boc-D-leucine is an N-Boc-protected form of D-Leucine (L330150). D-Leucine is an unnatural isomer of L-Leucine (L330110) that acts as an auto-inhibitor of lactic streptococci in culture. D-Leucine causes analgesia in humans and also exhibits inhibitory activity in bacterial cell cultures.