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2-Methylaziridin
PROPYLENEIMINE · PtdIns · Aziridine, 2-methyl- · Propylenimine · 1,2-Propylenimine · A1A · DFN7 · GST3
Identifikatoren & physikalische Daten
| CAS No. | 75-55-8 |
|---|---|
| Summenformel | C3H7N |
| Durchschnittliche Molmasse | 57,09 g/mol |
| Monoisotopische Masse | 57,05784922 g/mol |
| SMILES | CC1CN1 |
| InChIKey | OZDGMOYKSFPLSE-UHFFFAOYSA-N |
| PubChem CID | 6377 |
| ChEMBL | CHEMBL3183775 |
| ChEBI | CHEBI:82340 |
| EC No. | 200-878-7 |
| DTXSID | DTXSID8024286 |
| Lokaler Name | 2-Methylaziridin |
Chemische & physikalische Eigenschaften
| XLogP | 0 |
|---|---|
| Polarare Oberfläche (TPSA) | 21,9 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 4 |
| Formalladung | 0 |
| Komplexität | 26,5 |
| Stoffklassen | Hazardous Air Pollutants (HAPs)Nitrogen Compounds -> Other Nitrogen CompoundsCarcinogens |
| Pestizide | Pesticide -> EPA IRIS |
| LogP (Verteilungskoeffizient) | 0.13 |
| Geruch | Odor like aliphatic aminesAmmonia-like odor |
| Dichte | 0.8039 to 0.807 at 77 °F (EPA, 1998)0.8039-0.8070 at 25 °C/25 °CRelative density (water = 1): 0.80.8039-0.807 at 77 °F0.812 @ 16°C |
| Viscosity | 0.491 cP at 25 °C0.6 mm²/s at 25 °C |
| Color/Form | Colorless, oily liquid |
| Löslichkeit | greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)In water, miscible in all proportionsSoluble in ethanolSoluble in most organic solventsSolubility in water: misciblesoluble in No data available |
| Flammpunkt | 25 °F (EPA, 1998)-3 °C-3.9 °C, closed cup-18 °C c.c.-4°C |
| Siedepunkt | 151 to 153 °F at 760 mmHg (EPA, 1998)67 °C152 °F67 °C @760 [mm Hg]66°C |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxide/. |
| Schmelzpunkt | -85 °F (EPA, 1998)-65 °C-63 °C-65°C |
| Brechungsindex | 1.4125 |
| Lagerbedingungen | -20°C |
| pKa (Säurekonstante) | pK1:8.18(+1) (25°C) |
| Aggregatzustand | Flammable liquid |
| Henry-Konstante | 9.9×10-1 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) |
| Stabilität | Unstable - readily polymerises in the absence of an inhibitor. May polymerize vigorously or explosively in the presence of acids. Flammable. Incompatible with acids, oxidizing agents, quinones, carbonyl compounds, sulfonyl halides, some types of plastic, water. |
| CAS Datenbank | 75-55-8(CAS DataBase Reference) |
| NIST chemische Informationen | Aziridine, 2-methyl-(75-55-8) |
| EPA chemische Informationen | Propyleneimine (75-55-8) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH225: Highly Flammable liquid and vapor [Danger Flammable liquids]P203, P210, P233, P240, P241, P242, P243, P260, P262, P264, P264+P265, P270, P271, P273, P280, P284, P301+P316, P302+P352, P303+P361+P353, P304+P340, P305+P354+P338, P316, P317, P318, P320, P321, P330, P361+P364, P370+P378, P391, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 0.3% (1 of 362) of reports.H225 (99.7%): Highly Flammable liquid and vapor [Danger Flammable liquids] |
|---|---|
| Regulatorische Informationen | Chemical: Aziridine, 2-methyl-Hazard Traits - CarcinogenicityDermatotoxicityHepatotoxicity and Digestive System ToxicityNephrotoxicity and Other Toxicity to the Urinary SystemOcular ToxicityRespiratory ToxicityAziridine, 2-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Aziridine, 2-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 28-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/13279Propylene imine: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| Weitere Sicherheitsinformationen | IMAP assessments - Aziridines: Human health tier II assessment |
| DOT-Kennzeichnung | Flammable Liquid Poison |
| Brandgefahren | Chemical is extremely flammablevapors are heavier than air. Toxic oxides of nitrogen are produced during combustion. Avoid acids, strong oxidizers. Thermally unstable. Hazardous polymerization may occur. Contact with acid promotes violent polymerization. (EPA, 1998)· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. |
Anwendungen & Verwendung
Verwenden
The renal papillary toxin.