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HCID 638024Erstellt: 1. November 2026

Piperine

5-stilbenediol · (E/Z)-Piperine · SichuanPepper oil · 1-piperoylpiperidine (Standard) · 1-piperoylpiperidine, 10 mM in DMSO · 1-Piperidino-5-(1,3-benzodioxole-5-yl)-2,4-pentadiene-1-one · 1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine · 2,4-Pentadien-1-one, 5-(1,3-benzodioxol-5-yl)-1-(1-piperidinyl)-

https://huagongshe.com/de/chemical/638024

Identifikatoren & physikalische Daten

CAS No.	7780-20-3
Summenformel	C17H19NO3
Durchschnittliche Molmasse	285,34 g/mol
Monoisotopische Masse	285,13649347 g/mol
SMILES	O=C(/C=C/C=C/c1ccc2c(c1)OCO2)N1CCCCC1
InChIKey	MXXWOMGUGJBKIW-YPCIICBESA-N
PubChem CID	638024
ChEMBL	CHEMBL43185
ChEBI	CHEBI:28821
EC No.	202-348-0
DTXSID	DTXSID3021805

Chemische & physikalische Eigenschaften

XLogP	3,5
Polarare Oberfläche (TPSA)	38,8
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	3
Frei drehbare Bindungen	3
Schwere Atome	21
Formalladung	0
Komplexität	412
Stoffklassen	Other Uses -> Food Additives
Arzneimittel	Pharmaceuticals -> Listed in ZINC15
SpringerMaterials Properties	Viscosity
Duftstoffe	Fragrance Ingredient (Piperine) -> IFRA transparency List
Lebensmittelzusatzstoffe	FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Aromastoffe	EU Flavoring substances
Löslichkeit	0.04 mg/mL at 18 °CVery slightly soluble in waterSoluble in ether, oilsSoluble (in ethanol)
Human Drugs	Breast FeedingLactationMilk, HumanCytochrome P-450 Enzyme Inhibitors
Siedepunkt	498.00 to 499.00 °C. @ 760.00 mm Hg498.5±40.0 °C(Predicted)
Schmelzpunkt	129 °C
Dampfdruck	0.00000013 [mmHg]
Physical Description	Light yellow to yellow solid with a pungent odor[Reference #1] Light yellow solid[Sigma-Aldrich MSDS]Virtually colourless white crystalsAroma reminiscent of pepper
Dichte	1.211±0.06 g/cm3(Predicted)
Lagerbedingungen	Store at room temperature
pKa (Säurekonstante)	-0.71±0.20(Predicted)
InChI	InChI=1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2
InChIKey	MXXWOMGUGJBKIW-UHFFFAOYSA-N
SMILES	C(N1CCCCC1)(=O)C=CC=CC1=CC=C2OCOC2=C1
LogP (Verteilungskoeffizient)	3.365 (est)

Sicherheit & Vorschriften

GHS-Einstufung	DangerH301 (93.4%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 1804 reports by companies from 7 notifications to the ECHA C&L Inventory.
Regulatorische Informationen	Chemical: Piperidine, 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-, (E,E)-Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Piperine: Does not have an individual approval but may be used under an appropriate group standard
Gefahrenübersicht	A mild skin and eye irritant[Reference #1] Safe when used as a flavoring agent in food[JECFA] May cause irritationHarmful by ingestion[Sigma-Aldrich MSDS]
Hazard Classes and Categories	Acute Tox. 3 (93.4%)
Effects During Pregnancy and Lactation	◉ Summary of Use during Lactation

Piperine

CAS No.

7780-20-3

Summenformel

C17H19NO3

Durchschnittliche Molmasse

285,34 g/mol

Monoisotopische Masse

285,13649347 g/mol

SMILES

O=C(/C=C/C=C/c1ccc2c(c1)OCO2)N1CCCCC1

InChIKey

MXXWOMGUGJBKIW-YPCIICBESA-N

PubChem CID

638024

ChEMBL

CHEMBL43185

ChEBI

CHEBI:28821

EC No.

202-348-0

DTXSID

DTXSID3021805

Chemische & physikalische Eigenschaften

XLogP

3,5

Polarare Oberfläche (TPSA)

38,8

H-Brücken-Donoren

H-Brücken-Akzeptoren

Frei drehbare Bindungen

Schwere Atome

Formalladung

Komplexität

412

Stoffklassen

Other Uses -> Food Additives

Arzneimittel

Pharmaceuticals -> Listed in ZINC15

SpringerMaterials Properties

Viscosity

Duftstoffe

Fragrance Ingredient (Piperine) -> IFRA transparency List

Lebensmittelzusatzstoffe

FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food

Aromastoffe

EU Flavoring substances

Löslichkeit

0.04 mg/mL at 18 °CVery slightly soluble in waterSoluble in ether, oilsSoluble (in ethanol)

Human Drugs

Breast FeedingLactationMilk, HumanCytochrome P-450 Enzyme Inhibitors

Siedepunkt

498.00 to 499.00 °C. @ 760.00 mm Hg498.5±40.0 °C(Predicted)

Schmelzpunkt

129 °C

Dampfdruck

0.00000013 [mmHg]

Physical Description

Light yellow to yellow solid with a pungent odor[Reference #1] Light yellow solid[Sigma-Aldrich MSDS]Virtually colourless white crystalsAroma reminiscent of pepper

Dichte

1.211±0.06 g/cm3(Predicted)

Lagerbedingungen

Store at room temperature

pKa (Säurekonstante)

-0.71±0.20(Predicted)

InChI

InChI=1S/C17H19NO3/c19-17(18-10-4-1-5-11-18)7-3-2-6-14-8-9-15-16(12-14)21-13-20-15/h2-3,6-9,12H,1,4-5,10-11,13H2

InChIKey

MXXWOMGUGJBKIW-UHFFFAOYSA-N

SMILES

C(N1CCCCC1)(=O)C=CC=CC1=CC=C2OCOC2=C1

LogP (Verteilungskoeffizient)

3.365 (est)

Sicherheit & Vorschriften

GHS-Einstufung

DangerH301 (93.4%): Toxic if swallowed [Danger Acute toxicity, oral]P264, P270, P301+P316, P321, P330, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 1804 reports by companies from 7 notifications to the ECHA C&L Inventory.

Regulatorische Informationen

Chemical: Piperidine, 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]-, (E,E)-Commission Regulation (EC) No 1565/2000 (Repealed by Com. Implementing Reg. (EU) No 872/2012)Piperine: Does not have an individual approval but may be used under an appropriate group standard

Gefahrenübersicht

A mild skin and eye irritant[Reference #1] Safe when used as a flavoring agent in food[JECFA] May cause irritationHarmful by ingestion[Sigma-Aldrich MSDS]

Hazard Classes and Categories

Acute Tox. 3 (93.4%)

Effects During Pregnancy and Lactation

◉ Summary of Use during Lactation