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Chlortrimethylsilan
TMSCL · 75-77-4 · CSI · TMCS · TRIMETHYLSILYL CHLORIDE · TRIMETHYLCHLOROSILANE · tmsci · (CH3)3SiCl
Identifikatoren & physikalische Daten
| CAS No. | 75-77-4 |
|---|---|
| Summenformel | C3H9ClSi |
| Durchschnittliche Molmasse | 108,64 g/mol |
| Monoisotopische Masse | 108,0162045 g/mol |
| SMILES | C[Si](C)(C)Cl |
| InChIKey | IJOOHPMOJXWVHK-UHFFFAOYSA-N |
| PubChem CID | 6397 |
| ChEMBL | CHEMBL1505385 |
| ChEBI | CHEBI:85069 |
| EC No. | 200-900-5 |
| DTXSID | DTXSID2024822 |
| Lokaler Name | Chlortrimethylsilan |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 0 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 28 |
| Schmelzpunkt | −40 °C(lit.) |
| Siedepunkt | 57 °C(lit.) |
| Dichte | 0.857 g/mL at 25 °C |
| Dampfdichte | 3.7 (vs air) |
| Dampfdruck | 100 mm Hg ( 25 °C) |
| Brechungsindex | n20/D 1.500 |
| Flammpunkt | 104 °F |
| Lagerbedingungen | Store below +30°C. |
| Löslichkeit | Miscible with ether, benzene, diethylether and perchloroethylene.REACTS |
| Aggregatzustand | Liquid |
| Wichte | 0.8536 (27℃) |
| Farbe | Clear colorless |
| Explosionsgrenze | 1.5-46%(V) |
| BRN | 1209232 |
| Stabilität | Stable. Highly flammable - note low flash point. Reacts violently with water. Incompatible with water, moisture, strong oxidizing agents, strong acids, strong bases, aldehydes, alcohols, amines, esters, ketones. |
| InChI | 1S/C3H9ClSi/c1-5(2,3)4/h1-3H3 |
| InChIKey | IJOOHPMOJXWVHK-UHFFFAOYSA-N |
| SMILES | C[Si](C)(C)Cl |
| CAS Datenbank | 75-77-4(CAS DataBase Reference) |
| NIST chemische Informationen | Silane, chlorotrimethyl-(75-77-4) |
| EPA chemische Informationen | Trimethylchlorosilane (75-77-4) |
Sicherheit & Vorschriften
| F | 10-21 |
|---|---|
| Wassergefährdungsklasse (WGK) | 2 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 1298 |
| Zollcode | 29310095 |
| RTECS-Nr. | VV2710000 |
| R-Sätze (R) | 20/21-36/38-34-21-14-11-37-35-19-40-10-67-20/21/22-52 |
| Toxizität | LD50 orally in Rabbit: 4868 mg/kg LD50 dermal Rabbit 1530 mg/kg |
| Gefahrensymbole | T,F,C,Xn |
| hazard_note | Highly Flammable/Corrosive/Moisture Sensitive |
| Sicherheitshinweise (S) | 26-36/37/39-45-16-36/37-7/9 |
| Gefahrenklasse | 3Acute Tox. 3 InhalationAcute Tox. 3 OralAcute Tox. 4 DermalEye Dam. 1Flam. Liq. 2Skin Corr. 1A |
| Verpackungsgruppe | II |
| Lagerklasse | 3 - Flammable liquids |
| Gefahrstoffdaten | 75-77-4(Hazardous Substances Data) |
| Selbstentzündungstemperatur | 752 °F |
Anwendungen & Verwendung
Verwenden
Chlorotrimethylsilane is a typical Silane Blocking Agent, which can protect or deprotect functional groups selectively. It have been used in the preparation of volatile derivatives of a wide range of compounds for GC analysis, and used for silylation and as a protection group in the process of various organic synthesis. It is used in the production of trimethylsilyl halides, pseudohalides and various organic silicon compounds. It is also used to produce hexamethyldisilane by reduction.