HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Mangandibromid
MnBr2 · MANGANESE BROMIDE · MANGANESE (II) BROMIDE · Manganousbromide · Dibromomanganese · Manganous bromide · anese(II) bromide · Managanese bromide
Identifikatoren & physikalische Daten
| CAS No. | 13446-03-2 |
|---|---|
| Summenformel | Br2Mn |
| Durchschnittliche Molmasse | 214,75 g/mol |
| SMILES | [Br-].[Br-].[Mn+2] |
| InChIKey | RJYMRRJVDRJMJW-UHFFFAOYSA-L |
| PubChem CID | 6432071 |
| EC No. | 236-591-9 |
| Lokaler Name | Mangandibromid |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 0 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 3 |
| Formalladung | 0 |
| Komplexität | 0 |
| Schmelzpunkt | 698°C |
| Dichte | 4.385 g/mL at 25 °C(lit.) |
| Aggregatzustand | Powder |
| Wichte | 4.38 |
| Farbe | Pink |
| Löslichkeit | Soluble in water. (1273g/L) |
| Merck | 14,5725 |
| Stabilität | Stable, but very hygroscopic. Incompatible with strong oxidizing agents. Store under a dry atmosphere. |
| Hauptanwendungen | battery precursorscatalystsmaterial synthesis precursor |
| InChI | InChI=1S/2BrH.Mn/h2*1H/q+2/p-2 |
| InChIKey | RJYMRRJVDRJMJW-UHFFFAOYSA-L |
| SMILES | [Mn](Br)Br |
| CAS Datenbank | 13446-03-2(CAS DataBase Reference) |
| NIST chemische Informationen | Manganese bromide(13446-03-2) |
| EPA chemische Informationen | Manganese bromide (MnBr2) (13446-03-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302+H312+H332 (34.1%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oralacute toxicity, dermalacute toxicity, inhalation]P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 85 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| Minimum Risk Level | Chronic Inhalation: 0.0003 mg/m3 (Manganese) (L134) |
| Treatment | EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. |
| Gesundheitliche Auswirkungen | Manganese mainly affects the nervous system and may cause behavioral changes and other nervous system effects, which include movements that may become slow and clumsy. This combination of symptoms when sufficiently severe is referred to as “manganism”. (L228) |
| Expositionspfade | Oral (L626)inhalation (L626)dermal (L626) |
| Toxizitätsübersicht | Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particularily the globus pallidus of the basal ganglia. It is believed that the manganese ion, Mn(II), enhances the autoxidation or turnover of various intracellular catecholamines, leading to increased production of free radicals, reactive oxygen species, and other cytotoxic metabolites, along with a depletion of cellular antioxidant defense mechanisms, leading to oxidative damage and selective destruction of dopaminergic neurons. In addition to dopamine, manganese is thought to perturbations other neurotransmitters, such as GABA and glutamate. In order to produce oxidative damage, manganese must first overwhelm the antioxidant enzyme manganese superoxide dismutase. The neurotoxicity of Mn(II) has also been linked to its ability to substitute for Ca(II) under physiological conditions. It can enter mitochondria via the calcium uniporter and inhibit mitochondrial oxidative phosphorylation. It may also inhibit the efflux of Ca(II), which can result in a loss of mitochondrial membrane integrity. Mn(II) has been shown to inhibit mitochondrial aconitase activity to a significant level, altering amino acid metabolism and cellular iron homeostasis. Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and produce tissue damage. In additon, the formation of hydrobromic and bromic acids will result in secondary irritation. The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in the in actions of neurotransmitters and transport systems, thus affecting numerous synaptic processes. (L626, L627, A543, L228) |
Anwendungen & Verwendung
Verwenden
It can be used in place ofpalladiumin theStille reaction, which couples two carbon atoms using anorganotin compound.