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Grundinformationen
- CAS
1405-53-4- Standard-SMILES
CC[C@H]1OC(=O)C[C@@H](O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](O)[C@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC.O=P(O)(O)O- InChIKey
NBOODGNJLRRJNA-DRHKFUGVNA-N- Summenformel
- C46H80NO21P
- Durchschnittliche Molmasse
- 1.014,11 g/mol
Namen und Bezeichner
- Bevorzugter Name
- Tylosin phosphate
- Lokaler Name
- Tylosin, Phosphat (Salz)
- Englischer Name
- Tylosin phosphate
- Summenformel
- C46H80NO21P
- Molmasse
- 1014.11
Namen und Synonyme
TYLANFarmazin TBPharmasine TBosin phosphateTylan 40 premixTylan 10 premixylosin phosphateEinecs 215-779-4TYLOSIN PHOSPHATETylosinPhosphate80%
Datenbank-Bezeichner
- CAS
1405-53-4- PubChem CID
- 6440844
- ChEMBL
CHEMBL1888653- UNII
- NR75X12AFF
- EC Number
- 215-779-4
Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 128 °C · >128°C (dec.)
- storage temp.
- 2 · 2-8°C
- Löslichkeit
- Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- Farbe
- Pale Yellow
- Stabilität
- Hygroscopic
- Major Application
- clinical testing
- InChIKey
- NBOODGNJLRRJNA-DRHKFUGVNA-N
- CAS Datenbank
- 1405 · 1405-53-4(CAS DataBase Reference)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- 2
- RTECS-Nr.
- YP0625000
- Toxizität
- Tylosin base and its salts were shown to be of low acute oral toxicity with LD50 values in excess 5000 mg/kg bw in the rat and mouse and greater than 800 mg/kg bw in the dog.
- Speicherklasse
- 11 - Combustible Solids
- Hazard Classifications
- Resp. Sens. 1Skin Sens. 1
Chemie und Industrie
Anwendungen
HistoryTylosin phosphate is a macrolide antibiotic that was isolated and identified in 1959 by American scientists McGuire, Hamill, et al. from the fermentation broth of Streptomyces fradiae. As a secondary metabolite of this bacterium, it was subsequently produced industrially via fermentation by Eli Lilly and Company in Indiana, USA. The phosphate and tartrate salts of tylosin are currently the most commonly used forms in clinical practice. Although tylosin can also be produced by other bacterial strains, such as Streptomyces rimosus and Streptomyces hygroscopicus, Streptomyces fradiae remains the preferred strain for its industrial fermentation production.
VerwendenTylosin phosphate is a pure-grade antibiotic that was designated as a feed additive as of July 24, 1976. It is used for prevention and control of chronic respiratory disease (CRD) in replacement pullets, broilers, increasing bodyweight and improvement of feed conversion rate in broilers, increasing egg production.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter100 Anbieter
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
湖南韵邦生物科技股份有限公司0731-88532326 13319508186 · [email protected]
南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
湖北威德利化学试剂有限公司186-02735115 18062128043 · [email protected]
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