Tylosin, 3-Acetat-4B-(3-methylbutanoat)
Tylvalosin
Grundinformationen
- CAS
63409-12-1- Standard-SMILES
CC[C@H]1OC(=O)C[C@@H](OC(C)=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)[C@@H](O[C@H]3C[C@@](C)(O)[C@@H](OC(=O)CC(C)C)[C@H](C)O3)[C@H](N(C)C)[C@H]2O)[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(C)=C/[C@@H]1CO[C@@H]1O[C@H](C)[C@@H](O)[C@@H](OC)[C@H]1OC- InChIKey
KCJJINQANFZSAM-HZDSEHBESA-N- Summenformel
- C53H87NO19
- Durchschnittliche Molmasse
- 1.042,3 g/mol
- Monoisotopische Masse
- 1.041,58722956
Namen und Bezeichner
- Bevorzugter Name
- Tylvalosin
- IUPAC
- [(2S,3S,4R,6S)-6-[(2R,3S,4R,5R,6R)-6-[[(4R,5S,6S,7R,9R,11E,13E,15R,16R)-4-acetyloxy-16-ethyl-15-[[(2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl]oxymethyl]-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl]oxy]-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy-4-hydroxy-2,4-dimethyloxan-3-yl] 3-methylbutanoate
- Lokaler Name
- Tylosin, 3-Acetat-4B-(3-methylbutanoat)
- Englischer Name
- Tylosin, 3-acetate 4B-(3-methylbutanoate)
- Summenformel
- C53H87NO19
- Molmasse
- 1042.25
Namen und Synonyme
TYLVALOSIN63409-12-1tilvalosinatylvalosineTylosin acetate isovalerte9T02S42WQOTYLVALOSIN (EMA EPAR: VETERINARY)DTXSID901016510tylvalosinumAivlosin 17%RefChem:58239DTXCID301474699
Weitere Namen anzeigen
ACETYLISOVALERYLTYLOSINTiamphenicolTylvalosin (>Tylvalosin (>90%)Aivlosin，TylvalosinKCJJINQANFZSAM-XRMHJPERSA-N3-O-Acetyl-4''-O-isovaleryltylosinAcetylisovaleryltylosin/ tylvalosin
264-132-2((2S,3S,4R,6S)-6-((2R,3S,4R,5R,6R)-6-(((4R,5S,6S,7R,9R,11E,13E,15R,16R)-4-acetyloxy-16-ethyl-15-(((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methyloxan-2-yl)oxymethyl)-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-6-yl)oxy)-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl)oxy-4-hydroxy-2,4-dimethyloxan-3-yl) 3-methylbutanoateTYLOSIN ACETATE ISOVALERATETylvalosin [USAN]Tylvalosin [USAN:INN]EINECS 264-132-2UNII-9T02S42WQO3-Acetyl-4''-isovaleryltylosin
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 3,4
- Polarare Oberfläche (TPSA)
- 251 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 20
- Frei drehbare Bindungen
- 19
- Schwere Atome
- 73
- Formalladung
- 0
- Komplexität
- 1.860
Experimentelle und physikochemische Eigenschaften
Animal Drugs
EMA approved medicines: Veterinary medicine
Active Ingredients (Tylvalosin) -> FDA Greenbook
Pharmaceuticals -> UK Veterinary Medicines Directorate List
Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
Physikochemische Eigenschaften
- Schmelzpunkt
- 105 °C · >105°C (dec.)
- Siedepunkt
- 1005.4 · 1005.4±65.0 °C(Predicted)
- Dichte
- 1.21 · 1.21±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C Freezer, Under Inert Atmosphere
- Löslichkeit
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 13.06 · 13.06±0.70(Predicted)
- Aggregatzustand
- Solid
- Farbe
- Off-White to Pale Yellow
Chemie und Industrie
Pharmakologische Informationen
ATC CodeQJ - Antiinfectives for systemic use
Verwendung und Herstellung
Use Classification
Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients
Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
Anwendungen
VerwendenTylvalosin is an anti-bacterial agent that is shown through study as a good inhibitor of gram-positive bacteria.
Zugehörige Reaktionen
2
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