Herbicidin A
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
55353-31-6- Standard-SMILES
C/C=C(\CO)C(=O)O[C@H]1[C@H](O)[C@@H](C(=O)OC)O[C@@H]2C[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](OC)[C@H]3O[C@]21O- InChIKey
LOWKANMKNQBRPJ-MRAUHCMASA-N- Summenformel
- C23H29N5O11
- Durchschnittliche Molmasse
- 551,509 g/mol
- Monoisotopische Masse
- 551,18635675
Namen und Bezeichner
- Bevorzugter Name
- Herbicidin A
- IUPAC
- 9-{6,10-Anhydro-5-deoxy-8-O-[(2E)-2-(hydroxymethyl)but-2-enoyl]-11-methyl-2-O-methyl-beta-D-arabino-alpha-L-ido-undec-7-ulopyranosefuranosyluronosyl}-9H-purin-6-amine
- Englischer Name
- Herbicidin A
- Summenformel
- C23H29N5O11
- Molmasse
- 551.5
Namen und Synonyme
HerbicidinHerbicidin A(11R)-11-C-(6-Amino-9H-purin-9-yl)-2,6(11R)-11-C-(6-Amino-9H-purin-9-yl)-2,6:8,11-dianhydro-10-O-methyl-4-O-[(E)-1-oxo-2-(hydroxymethyl)-2-butenyl]-7-deoxy-α-L-ido-D-lyxo-5-undecoulo-5,9-pyranosonic acid methyl esterD-arabino-α-L-ido-7-Undeculo-7,3-pyranose-1,4-furanuronic acid, 1-(6-amino-9H-purin-9-yl)-6,10-anhydro-1,5-dideoxy-2-O-methyl-, methyl ester, 8-[(2E)-2-(hydroxymethyl)-2-butenoate], (7R)-
Datenbank-Bezeichner
- CAS
55353-31-6- PubChem CID
- 6441694
- DTXSID
DTXSID801317929- ChEMBL
CHEMBL3109448
Eigenschaften
Physikochemische Eigenschaften
- Siedepunkt
- 826.5 · 826.5±75.0 °C(Predicted)
- Dichte
- 1.78 · 1.78±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
- Aggregatzustand
- A solid
- pka
- 10.17 · 10.17±0.70(Predicted)
Chemie und Industrie
Anwendungen
BeschreibungHerbicidin A is an adenine nucleoside antibiotic originally isolated from S. saganonensis that exhibits herbicidal activity, particularly against dicotyledonous plants. It prevents rice seed germination (MIC = 6.25 μg/ml) and completely protects young rice plants from X. oryzae-induced leaf blight when applied at 100 ppm. In HEK293 cells, herbicidin A inhibits TNF-α-induced NF-κB activity and induces cytotoxicity (IC50s = 1.8 and 2.7 μM, respectively).
VerwendenHerbicidin A is the major analogue of a family of adenosine nucleosides containing a complex tricyclic saccharide originally isolated from Streptomyces saganonensis, reported by researchers at Sankyo in 1976. Hebicidin A is a potent herbicide with selective activity against dicotyledonous plants. The mode of action and broader pharmacology of herbicidin A has received little attention due to its restricted availability.
Anbieter15 Anbieter
上海赛可锐生物科技有限公司021-58000709 13120558703 · [email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
孟成科技（上海）有限公司400-820-6829 · [email protected]
上海维亦特生物科技有限公司15317051735 · [email protected]
成都润泽本土化工有限公司13096311329 028-88469284 616445927 · [email protected]
上海一研生物科技有限公司021-69985186 13611928337 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…