Eprinomectin
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Grundinformationen
- CAS
123997-26-2- Standard-SMILES
CO[C@H]1C[C@H](O[C@@H]2/C(C)=C\C[C@@H]3C[C@@H](C[C@]4(C=C[C@H](C)[C@@H](C(C)C)O4)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC/C(=C/C=C\[C@@H]2C)[C@]43O)O[C@@H](C)[C@H]1O[C@H]1C[C@@H](OC)[C@H](NC(C)=O)[C@H](C)O1- InChIKey
WPNHOHPRXXCPRA-TVXIRPTOSA-N- Summenformel
- C50H75NO14
- Durchschnittliche Molmasse
- 914,1288 g/mol
Namen und Bezeichner
- Bevorzugter Name
- Eprinomectin
- Englischer Name
- Eprinomectin
- Summenformel
- C50H75NO14
- Molmasse
- 914.1288
Namen und Synonyme
Emamectin B1 BenzoateeprinexEprinomectin (Mixture of B1a and B1b)MK 397EPRINOMECTINEprinomectionEprinomectinB1AcetaminobamectinAcetaminoabamectinacetamido abamectin
Datenbank-Bezeichner
- CAS
123997-26-2- PubChem CID
- 6450531
- ChEMBL
CHEMBL3989594- EC Number
- 602-966-4
Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 163 · 163-166°C
- Dichte
- 1.23 · 1.23
- Flammpunkt
- 2 °C · 2 °C
- storage temp.
- 2 · 2-8°C
- Löslichkeit
- 30 mg/ml; · DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml
- Aggregatzustand
- Solid
- Farbe
- White to off-white
- Stabilität
- Hygroscopic
- Major Application
- pharmaceutical (small molecule)
- InChIKey
- WPNHOHPRXXCPRA-TVXIRPTOSA-N
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- 3
- ridadr
- UN 2811
- hs_code
- 2941906000
- risk_code
- 11-20/21/22-36-62-50/53-25-63
- Toxizität
- LD50 orally in mice: 24 mg/kg (Jones)
- hazard_code
- F,Xn,N,T
- safety_code
- 26-36/37-16-61-60-45
- Speicherklasse
- 6.1C - Combustible acute toxic Cat.3toxic compounds or compounds which causing chronic effects
- Hazard Classifications
- Acute Tox. 3 OralAquatic Acute 1Aquatic Chronic 1Repr. 2
Chemie und Industrie
Anwendungen
BeschreibungEprinomectin is a semisynthetic avermectin that consists of a mixture of two homologues, eprinomectin B1a (4 epi-acetylamino-4 -deoxy-avermectin B1; 90%) and eprinomectin B1b (10%).Eprinomectin was developed as a topical endectocide for all categories of cattle including lactating dairy cattle, and the process by which eprinomectin was selected for further development has been described (90). Briefly, several hundred avermectin/ milbemycin analogues were screened in a sheep model for efficacy against a range of endoparasites and in lactating dairy cows for a low milk:plasma partitioning ratio. Themilk:plasma ratio for eprinomectin is
VerwendenEprinomectin is a mixture of eprinomectins B1a and B1b in a 9:1 ratio, produced from a mixture of avermectin B1a and B1b. Eprinomectin is used commercially as a topical endectocide (insecticide, miticide and nematocide) for cattle, including lactating dairy cows. Like all avermectins and milbemycins, eprinomectin acts by binding to parasite glutamate-gated chloride ion channels and disrupts neurotransmission leading to paralysis and death of the parasite, mite or insect.
Anbieter100 Anbieter
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
HubeiwidelychemicaltechnologyCo.,Ltd18627774460 · [email protected]
武汉灵灵九生物科技有限公司15623309010 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
河北展药生物科技有限公司15369953316 +8615369953316 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
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