Eprodisate Disodium
Daten werden ergänzt – meist innerhalb einer Minute fertig
Grundinformationen
- CAS
36589-58-9- Standard-SMILES
O=S(=O)([O-])CCCS(=O)(=O)[O-].[Na+].[Na+]- InChIKey
DKGJFKPIUSHDIT-UHFFFAOYSA-L- Summenformel
- C3H6Na2O6S2
- Durchschnittliche Molmasse
- 248,2 g/mol
- Monoisotopische Masse
- 247,94011847
Überblick
Eprodisate Disodium is the orally available disodium salt form of eprodisate, a negatively charged sulfonated inhibitor of fibrillogenesis, that can be used in the treatment of amyloid A (AA) amyloidosis. Upon administration, eprodisate competitively binds to the glycosaminoglycan binding sites on serum amyloid A (SAA), which inhibits the formation of the glycosaminoglycan-amyloid fibril aggregate. This prevents the formation of amyloid deposits in certain organs, especially the kidneys, in AA amyloidosis.
Namen und Bezeichner
- Bevorzugter Name
- Eprodisate Disodium
- IUPAC
- disodium;propane-1,3-disulfonate
Namen und Synonyme
Eprodisate disodium36589-58-9KiactaDisodium propane-1,3-disulfonateEprodisate sodium1,3-Propanedisulfonic acid, disodium saltNC-503Eprodisate Disodium [USAN]UNII-5X0D9H16IUNC 5035X0D9H16IUDTXSID9046732
Weitere Namen anzeigen
DISODIUM EPRODISATENSC-240395NSC-760403Eprodisate disodium (USAN)DTXCID7026732EPRODISATE DISODIUM [MART.]EPRODISATE DISODIUM [WHO-DD]NSC 240395
Datenbank-Bezeichner
- CAS
36589-58-9- PubChem CID
- 6451143
- DTXSID
DTXSID9046732- ChEMBL
CHEMBL2107338- UNII
- 5X0D9H16IU
- EC Number
- 621-789-3
- Nikkaji
- J534.156F
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- Polarare Oberfläche (TPSA)
- 131 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 13
- Formalladung
- 0
- Komplexität
- 227
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 44 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Zugehörige Reaktionen
5
Notizen zur Verbindung
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