Chlortriphenylsilan
Chlorotriphenylsilane · P3 · TRIPHENYLCHLOROSILANE · TPCS · MyD10 · ICAM-1/CD · TRIPHENLCHLOROSILANE · chlorotriphenyl-silan
Identifikatoren & physikalische Daten
| CAS No. | 76-86-8 |
|---|---|
| Summenformel | C18H15ClSi |
| Durchschnittliche Molmasse | 294,8 g/mol |
| Monoisotopische Masse | 294,0631547 g/mol |
| SMILES | Cl[Si](c1ccccc1)(c1ccccc1)c1ccccc1 |
| InChIKey | MNKYQPOFRKPUAE-UHFFFAOYSA-N |
| PubChem CID | 6458 |
| EC No. | 200-989-0 |
| DTXSID | DTXSID70870398 |
| Lokaler Name | Chlortriphenylsilan |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 0 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 3 |
| Schwere Atome | 20 |
| Formalladung | 0 |
| Komplexität | 240 |
| Kovats Retention Index | 2191 |
| Schmelzpunkt | 91-94 °C(lit.) |
| Siedepunkt | 378 °C |
| Dichte | 1.14 |
| Flammpunkt | >200°C |
| Lagerbedingungen | Refrigerator |
| Löslichkeit | acetone: 0.1 g/mL, clearReacts with water. |
| Aggregatzustand | crystal |
| Farbe | white |
| Wichte | 1.16 |
| BRN | 1820487 |
| InChI | 1S/C18H15ClSi/c19-20(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H |
| InChIKey | MNKYQPOFRKPUAE-UHFFFAOYSA-N |
| SMILES | Cl[Si](c1ccccc1)(c2ccccc2)c3ccccc3 |
| CAS Datenbank | 76-86-8(CAS DataBase Reference) |
| NIST chemische Informationen | Triphenylchlorosilane(76-86-8) |
| EPA chemische Informationen | Silane, chlorotriphenyl- (76-86-8) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H335 (80%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P260, P261, P264, P271, P280, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P319, P321, P363, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 50 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Chemical: Silane, chlorotriphenyl-Chlorotriphenylsilane: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Skin Corr. 1B (100%)STOT SE 3 (80%) |
| F | 10-21 |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 3261 8/PG 2 |
| Zollcode | 29310095 |
| RTECS-Nr. | VV2720000 |
| R-Sätze (R) | 34-37 |
| Gefahrensymbole | C |
| Sicherheitshinweise (S) | 26-36/37/39-45-24/25 |
| Gefahrenklasse | 8Skin Corr. 1B |
| Verpackungsgruppe | II |
| Lagerklasse | 8A - Combustible corrosive hazardous materials |
Anwendungen & Verwendung
Beschreibung
Triphenylsilyl chloride is a white to off-white crystal or powder with acrid ordor of hydrogen chloride, used for synthesis of pharmaceutical intermediates.
Verwenden
A wide variety of Grignard reagents and organolithium complexes participate in reactions with Ph3SiCl to afford organosilanes. Thus the reaction of allylmagnesium chloride with Ph3SiCl gives the allylsilane in high yield (eq 3).However, when hydrosilyl Grignard reagents are employed, reduction to the silane occurs (eq 4).Azaallyl anion6 and diazolithium salts can each be silylated to give the anticipated silane adducts (eqs 5 and 6). Similarly, arylsilanes8 and alkynylsilanes are produced upon silylation of the appropriate metalated13 carbanions with Ph3SiCl (eqs 7–11).