HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Dibrom-dimethylhydantoin
77-48-5 · DBDMH · DBNPA · 1,3-Dibromo-5,5-dimethylimidazolidine-2,4-dione · DDH · dibromohydantoin · DIBROMANTIN · dibromantine
Identifikatoren & physikalische Daten
| CAS No. | 77-48-5 |
|---|---|
| Summenformel | C5H6Br2N2O2 |
| Durchschnittliche Molmasse | 285,92 g/mol |
| Monoisotopische Masse | 283,87960163 g/mol |
| SMILES | CC1(C)C(=O)N(Br)C(=O)N1Br |
| InChIKey | VRLDVERQJMEPIF-UHFFFAOYSA-N |
| PubChem CID | 6479 |
| ChEMBL | CHEMBL3184055 |
| EC No. | 201-030-9 |
| DTXSID | DTXSID3035341 |
| Lokaler Name | Dibrom-dimethylhydantoin |
Chemische & physikalische Eigenschaften
| XLogP | 1,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 40,6 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 11 |
| Formalladung | 0 |
| Komplexität | 229 |
| Stoffklassen | Other Uses -> Biocides/Disinfectants |
| Food Contact Substances | FCS -> FDA Inventory of Effective Food Contact Substance (FCS) Notifications |
| Physical Description | Dry PowderLight yellow powder[Aldrich MSDS] |
| Schmelzpunkt | 197-199 °C (dec.)(lit.) |
| Siedepunkt | 250.2±23.0 °C(Predicted) |
| Dichte | 1.00 g/cm3 (25℃) |
| Brechungsindex | 1.6220 (estimate) |
| Flammpunkt | 155 °C |
| Lagerbedingungen | Store below +30°C. |
| Löslichkeit | 1g/lSoluble in Alcohol, Ether, Benzene. Insoluble in Water. |
| Aggregatzustand | Powder |
| pKa (Säurekonstante) | -3.44±0.40(Predicted) |
| Farbe | Cream or light yellow |
| Decomposition | 197-199 ºC |
| Merck | 14,3017 |
| BRN | 146024 |
| InChI | 1S/C5H6Br2N2O2/c1-5(2)3(10)8(6)4(11)9(5)7/h1-2H3 |
| InChIKey | VRLDVERQJMEPIF-UHFFFAOYSA-N |
| SMILES | CC1(C)N(Br)C(=O)N(Br)C1=O |
| CAS Datenbank | 77-48-5(CAS DataBase Reference) |
| EPA chemische Informationen | 1,3-Dibromo-5,5-dimethylhydantoin (77-48-5) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH272 (93.5%): May intensify fireoxidizer [Danger Oxidizing liquidsOxidizing solids]P210, P220, P260, P264, P264+P265, P270, P273, P280, P301+P316, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P321, P330, P332+P317, P337+P317, P362+P364, P363, P370+P378, P391, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 231 reports by companies from 22 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: 2,4-Imidazolidinedione, 1,3-dibromo-5,5-dimethyl-2,4-Imidazolidinedione, 1,3-dibromo-5,5-dimethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 2,4-Imidazolidinedione, 1,3-dibromo-5,5-dimethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 24-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/100891,3-Dibromo-5,5-dimethylhydantoin: Does not have an individual approval but may be used under an appropriate group standard |
| Gefahrenübersicht | Evidence of thyroid hypofunction in repeated dose study of rats[RTECS] Corrosive to skinNot sensitizing to guinea pigsHalohydantoins: The persistent metabolites, 5,5-Dimethylhydantoin (DMH) and 5-Ethyl-5-methylhydantoin (EMH), are used for developing toxicity data for this group of compoundsQuickly decomposed by water forming hypochlorous or hypobromous acid (the true biocidal agents) and DMH or EMHDMH/EMH: Sub-chronic, developmental, reproductive, and chronic toxicity animal studies have shown non-specific toxicity at high doses (no evidence of carcinogenicity, reproductive or developmental toxicity, and limited evidence of mutagenicity)[Reference #1] An oxidizer that can intensify fireCauses burnsInhalation may cause corrosive injuries to upper respiratory tract and lungsToxic by ingestion[Aldrich MSDS] See 1,3-Dichloro-5,5-dimethylhydantoin. |
| Hazard Classes and Categories | Ox. Sol. 3 (93.5%) |
| Treatment | EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. |
| Gesundheitliche Auswirkungen | Bromine vapour causes irritation and direct damage to the mucous membranes. Elemental bromine also burns the skin. The bromide ion is a central nervous system depressant and chronic exposure produces neuronal effects. This is called bromism and can result in central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia, loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, delirium, aggressiveness, and psychoses. (L625, L626, L627) |
| Unerwünschte Wirkungen | Dermatotoxin - Skin burns. |
| Expositionspfade | Oral (L626)inhalation (L626)dermal (L626) |
| Toxizitätsübersicht | Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and produce tissue damage. In additon, the formation of hydrobromic and bromic acids will result in secondary irritation. The bromide ion is also known to affect the central nervous system, causing bromism. This is believed to be a result of bromide ions substituting for chloride ions in the in actions of neurotransmitters and transport systems, thus affecting numerous synaptic processes. (L626, L627, A543) |
| Signs and Symptoms | Bromine vapour causes irritation and direct damage to the mucous membranes. Symptoms include lacrimation, rhinorrhoea, eye irritation with mucous secretions from the oropharyngeal and upper airways, coughing, dyspnoea, choking, wheezing, epistaxis, and headache. The bromide ion is a central nervous system depressant producing ataxia, slurred speech, tremor, nausea, vomiting, lethargy, dizziness, visual disturbances, unsteadiness, headaches, impaired memory and concentration, disorientation and hallucinations. This is called bromism. (L626, L627) |
| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
| Toxicity Data | LC50 (rat) = 510 - 2,020 mg/m3 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 3087 5.1/PG 2 |
| Zollcode | 29332100 |
| RTECS-Nr. | MU0686000 |
| R-Sätze (R) | 8-22-35-50/53-50-34 |
| Gefahrensymbole | O,C,N,Xi |
| hazard_note | Harmful/Irritant |
| Sicherheitshinweise (S) | 17-26-36/37/39-45-60-61 |
| Gefahrenklasse | 5.1Acute Tox. 3 OralAquatic Acute 1Aquatic Chronic 1Eye Dam. 1Ox. Sol. 3Skin Corr. 1BSkin Sens. 1 |
| Verpackungsgruppe | II |
| Lagerklasse | 5.1B - Oxidizing hazardous materials |
| Selbstentzündungstemperatur | 550°C |
Anwendungen & Verwendung
Beschreibung
1,3-Dibromo-5,5-dimethylhydantoin is an important chemical product and has been widely applied in chemical, pharmaceutical and agricultural industries with various kinds of advantages including excellent stability, high content of bromine and high reactive activity.
Verwenden
Brominating agent. Analytical reagent for determination of iodide and organic iodine, and for identification tests.