2-(4-Iodophenyl)-3-(4-nitrophe-nyl)-5-phenyl-tetrazoliumchlorid

INT · 2-(4-IODOPHENYL)-3-(4-NITROPHENYL)-5-PHENYLTETRAZOLIUM CHLORIDE · INT DYE · IntA.R. · INT CHLORIDE · 2-(p-iodophe · I.N.T. 95% AR · INT, 10 mM in DMSO

https://huagongshe.com/de/chemical/64957

Molekülstruktur von 2-(4-Iodophenyl)-3-(4-nitrophe-nyl)-5-phenyl-tetrazoliumchlorid

Identifikatoren & physikalische Daten

CAS No.	146-68-9
Summenformel	C19H13IN5O2.Cl
Durchschnittliche Molmasse	505,7 g/mol
Monoisotopische Masse	504,98025 g/mol
SMILES	O=[N+]([O-])c1ccc(-[n+]2nc(-c3ccccc3)nn2-c2ccc(I)cc2)cc1.[Cl-]
InChIKey	JORABGDXCIBAFL-UHFFFAOYSA-M
PubChem CID	64957
ChEMBL	CHEMBL272094
ChEBI	CHEBI:75421
EC No.	205-676-2
DTXSID	DTXSID30932744
Lokaler Name	2-(4-Iodophenyl)-3-(4-nitrophe-nyl)-5-phenyl-tetrazoliumchlorid

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)	80,4
H-Brücken-Donoren	0
H-Brücken-Akzeptoren	5
Frei drehbare Bindungen	3
Schwere Atome	28
Formalladung	0
Komplexität	497
Stoffklassen	Other Uses -> Biochemical Research
Physical Description	Yellow powder[Alfa Aesar MSDS]
Schmelzpunkt	240 °C (dec.)(lit.)
Lagerbedingungen	2-8°C
Löslichkeit	methanol: water (1:1): 50 mg/mL hot, very faintly turbid, very deep yellowsoluble
Aggregatzustand	Powder, Crystals and/or Chunks
Farbe	White to off-white
BRN	4093224
Stabilität	Stable. Incompatible with strong oxidizing agents.
InChI	InChI=1S/C19H13IN5O2.ClH/c20-15-6-8-16(9-7-15)23-21-19(14-4-2-1-3-5-14)22-24(23)17-10-12-18(13-11-17)25(26)27/h1-13H1H/q+1/p-1
InChIKey	JORABGDXCIBAFL-UHFFFAOYSA-M
SMILES	[N+]1(=NC(C2C=CC=CC=2)=NN1C1C=CC(I)=CC=1)C1=CC=C([N+]([O-])=O)C=C1.[Cl-]
CAS Datenbank	146-68-9(CAS DataBase Reference)
EPA chemische Informationen	2H-Tetrazolium, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-, chloride (146-68-9)

Sicherheit & Vorschriften

Verpackungsgruppe
GHS-Einstufung	This chemical does not meet GHS hazard criteria for 21.4% (3 of 14) of reports.DangerH228 (14.3%): Flammable solid [Danger Flammable solids]P210, P240, P241, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 14 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Regulatorische Informationen	Chemical: 2H-Tetrazolium, 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-, chloride2-(4-Iodophenyl)-3-(4-nitrophenyl) 5-phenyltetrazolium chloride: Does not have an individual approval but may be used under an appropriate group standard
Gefahrenübersicht	A skin and strong eye irritantToxic by ingestionMay cause dermal photosensitivity sensitization and discoloration[Alfa Aesar MSDS] No articles on photosensitization found in search for 146-68-9 AND (allergic OR dermatitis OR sensiti*)[PubMed]
Hazard Classes and Categories	Flam. Sol. 1 (14.3%)
F	3-8-10
Wassergefährdungsklasse (WGK)	3
TSCA-Inventar-Status	TSCA listed
UN-Transportnummer	2811
Zollcode	29339900
R-Sätze (R)	20/21/22-68/20/21/22-36/37/38-11
Gefahrensymbole	Xn,F,Xi
Sicherheitshinweise (S)	36/37-36/37/39-26-22-16
Gefahrenklasse	6.1Flam. Sol. 1STOT SE 2STOT SE 3

Anwendungen & Verwendung

Beschreibung

Iodonitrotetrazolium (INT) (chloride) is a monotetrazolium salt used as an indicator dye. It is reduced to an insoluble formazan that is used as a vital dye or indicator of cellular redox activity. Reduction commonly results from the activity of dehydrogenases, although non-enzymatic electron transfer reactions can occur in the presence of an intermediate electron acceptor. INT is commonly used to measure the respiratory activity of microorganisms in a variety of contexts.

Verwenden

Iodonitrotetrazolium chloride has been used for the staining of cells. It has been used as a coupling agent in the enzymatic assay of D-arabinitol.