2,2'-Dithiodipyridin
2,2'-Dipyridyl disulfide
Grundinformationen
- CAS
2127-03-9- Standard-SMILES
c1ccc(SSc2ccccn2)nc1- InChIKey
HAXFWIACAGNFHA-UHFFFAOYSA-N- Summenformel
- C10H8N2S2
- Durchschnittliche Molmasse
- 220,3 g/mol
- Monoisotopische Masse
- 220,01289026
Überblick
Aldrithiol is a member of the class of pyridines that is pyridine which is substituted by a pyridin-2-yldisulfanediyl group at position 2. It is a reagent used in molecular biology as an oxidizing agent. Also used in peptide synthesis and for detecting thiols. It has a role as an oxidising agent. It is a member of pyridines and an organic disulfide.
Namen und Bezeichner
- Bevorzugter Name
- 2,2'-Dipyridyl disulfide
- IUPAC
- 2-(pyridin-2-yldisulfanyl)pyridine
- Lokaler Name
- 2,2'-Dithiodipyridin
- Englischer Name
- 2,2'-Dithiodipyridine
- Summenformel
- C10H8N2S2
- Molmasse
- 220.31
Namen und Synonyme
2,2'-Dithiodipyridine2127-03-92,2'-Dipyridyl disulfide2-(pyridin-2-yldisulfanyl)pyridine2,2'-Dipyridyldisulfide2-Dipyridyl disulfide2PDS2,2'-DithiopyridinePyridine, 2,2'-dithiobis-L6X912UPBUorthopyridyl disulfideDTXSID70175517
Weitere Namen anzeigen
Aldrithiol2-PDSDithiodipyridine2-AldrithiolDipyridyldisulfide2-Pyridyl disulfide
2,2-dithiobispyridine2,2-PDSRefChem:440289DTXCID5098008218-343-11,2-di(pyridin-2-yl)disulfaneAldrithiol-2Aldrithiol 2
Datenbank-Bezeichner
- CAS
2127-03-9- PubChem CID
- 65093
- DTXSID
DTXSID70175517- ChEMBL
CHEMBL118678- ChEBI
CHEBI:143170
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 2,6
- Polarare Oberfläche (TPSA)
- 76,4 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 3
- Schwere Atome
- 14
- Formalladung
- 0
- Komplexität
- 148
Experimentelle und physikochemische Eigenschaften
Chemical ClassesNitrogen Compounds -> Pyridines
Solubility25.5 [ug/mL] (The mean of the results at pH 7.4)
Melting Point58 °C
Physical DescriptionWhite crystalline powder; [Alfa Aesar MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 56 · 56-58 °C(lit.)
- Siedepunkt
- 356.1 · 356.1±17.0 °C(Predicted)
- Dichte
- 1.3078 · 1.3078 (rough estimate)
- Brechungsindex
- 1.55 · 1.5500 (estimate)
- Flammpunkt
- 210 °C · 210 °C
- storage temp.
- 2 · 2-8°C
- Löslichkeit
- 50 mg/mL, · methanol: soluble50mg/mL, clear to very slightly hazy, colorless to faintly brownish-yellow
- Aggregatzustand
- powder
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 1.5% (1 of 66) of reports.
Warning
H315 (98.5%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 66 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.
Pyridine, 2,2'-dithiobis-: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryA skin and strong eye irritant; [Alfa Aesar MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (98.5%)
Sicherheit und Schutzausrüstung
Protective Action Criteria (PAC)
12 [mg/m3]
130 [mg/m3]
790 [mg/m3]
Sicherheitsdaten
- F
- 10-23
- wgk
- 3
- tsca
- TSCA listed
- ridadr
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationElectron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION).
Verwendung und Herstellung
General Manufacturing InformationPyridine, 2,2'-dithiobis-: ACTIVE
Anwendungen
Verwenden2,2'-Dipyridyldisulfide, sometimes known as DPS, is used for preparing thiols and activating or protecting carboxylic acid with triphenylphosphine.
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