5-Brom-4-chlorindol-3-yl-beta-D-galactopyranosid

X-Gal

HCID 65181CAS 7240-90-6
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Grundinformationen

Standard-SMILES
OC[C@H]1O[C@@H](Oc2c[nH]c3ccc(Br)c(Cl)c23)[C@H](O)[C@@H](O)[C@H]1O
InChIKey
OPIFSICVWOWJMJ-AEOCFKNESA-N
Summenformel
C14H15BrClNO6
Durchschnittliche Molmasse
408,63 g/mol
Monoisotopische Masse
406,97713

Namen und Bezeichner

Bevorzugter Name
X-Gal
IUPAC
(2S,3R,4S,5R,6R)-2-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol
Lokaler Name
5-Brom-4-chlorindol-3-yl-beta-D-galactopyranosid
Englischer Name
5-Bromo-4-chloro-3-indolyl-beta-D-galactoside
Summenformel
C14H15BrClNO6
Molmasse
408.63

Namen und Synonyme

X-Gal7240-90-65-Bromo-4-chloro-3-indolyl beta-galactosideV595OG374W5-bromo-4-chloro-1H-indol-3-yl beta-D-galactopyranoside5-bromo-4-chloroindol-3-yl beta-D-galactopyranosidebeta-D-Galactopyranoside, 5-bromo-4-chloro-1H-indol-3-ylRefChem:1021685-bromo-4-chloro-3-indolyl-beta D-galactopyranoside230-640-85-Bromo-4-chloro-3-(beta-D-galactopyranosyloxy)indoleBCIG
Weitere Namen anzeigen
X-β-GAL5-BROMO-4-CHLORO-3-INDOLYL-β-D-GALACTOPYRANOSIDE (X-GAL)Bromo Dβ-D-GaLabs9126X-BETA-GALX-gal/BCIGoro-3-indoL
5-Bromo-4-chloro-3-indolyl-beta-D-galactosideMFCD000056665-Bromo-4-chloro-3-indolyl beta-D-galactopyranosideC14H15BrClNO6(2S,3R,4S,5R,6R)-2-[(5-bromo-4-chloro-1H-indol-3-yl)oxy]-6-(hydroxymethyl)oxane-3,4,5-triol5-Bromo-4-chloroindol-3-yl-beta-D-galactopyranoside.beta.-D-Galactopyranoside, 5-bromo-4-chloro-1H-indol-3-ylM02699

Datenbank-Bezeichner

CAS
7240-90-6
PubChem CID
65181
DTXSID
DTXSID901349452
ChEMBL
CHEMBL1242856
ChEBI
CHEBI:75055
UNII
V595OG374W
EC Number
230-640-8
Nikkaji
J212.257J

Eigenschaften

Berechnete Struktureigenschaften

XLogP
1,2
Polarare Oberfläche (TPSA)
115 Ų
H-Brücken-Donoren
5
H-Brücken-Akzeptoren
6
Frei drehbare Bindungen
3
Schwere Atome
23

Experimentelle und physikochemische Eigenschaften

Physical DescriptionSolid; [Merck Index] White powder; [Sigma-Aldrich MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
230 °C · 230 °C
Siedepunkt
673.9 · 673.9±55.0 °C(Predicted)
Dichte
1.5563 · 1.5563 (rough estimate)
Brechungsindex
1.611 · 1.6110 (estimate)
storage temp.
-20 °C · -20°C
Löslichkeit
100 mM · Soluble in 100 mM in DMSO.

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

This chemical does not meet GHS hazard criteria for 20% (2 of 10) of reports.

Warning

H302 (80%): Harmful if swallowed [Warning Acute toxicity, oral]；H312 (80%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H332 (80%): Harmful if inhaled [Warning Acute toxicity, inhalation]

P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 10 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 2 of 10 reports by companies.；There are 2 notifications provided by 8 of 10 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information5-Bromo-4-chloro-3-indolyl-beta-D-galactoside: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryMay cause irritation; [Sigma-Aldrich MSDS] See Indole and 5-Bromo-4-chloro-3-indoxyl phosphate.
Hazard Classes and CategoriesAcute Tox. 4 (80%)；Acute Tox. 4 (80%)；Acute Tox. 4 (80%)

Regulatorische Informationen

Regulatory Information5-Bromo-4-chloro-3-indolyl-beta-D-galactoside: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

F
8-10-21
wgk
3
hs_code
29389090
risk_code
36/37/38
hazard_code
Xi
safety_code
24/25-37/39-26

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 1 Eintrag

Colorless, endogenous or exogenous pigment precursors that may be transformed by biological mechanisms into colored compounds; used in biochemical assays and in diagnosis as indicators, especially in the form of enzyme substrates. Synonym: chromogens (not to be confused with pigment-synthesizing bacteria also called chromogens).

Verwendung und Herstellung

UsesChromogenic substrate of beta-galactosidase used in histological staining and cloning experiments of bacteria; [Merck Index]

Anwendungen

VerwendenA substrate for -Galactosidase that is converted by the enzyme into an intense indigo-blue chromophore (615 nm)

Anbieter50 Anbieter

北京华美互利生物化工010-56205725 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
南京百芙利科技有限责任公司25-25-58740604 15951658055 · [email protected]
Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: An indolyl carbohydrate that is the beta-D-galactoside of 3-hydroxy-1H-indole in which the indole moiety is substituted at positions 4 and 5 by chlorine and bromine, respectively. It is used to test for he presence of an enzyme, beta-galactosidase, which cleaved the glycosidic bond to give 5-bromo-4-chloro-3-hydroxy-1H-indole, which immediately dimerises to give an intensely blue product.

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