Grundinformationen
- CAS
151-06-4- Standard-SMILES
CC(C)(N)Cc1ccc(Cl)cc1.Cl- InChIKey
WEJDYJKJPUPMLH-UHFFFAOYSA-N- Summenformel
- C10H15Cl2N
- Durchschnittliche Molmasse
- 220,14 g/mol
- Monoisotopische Masse
- 219,0581549
Überblick
Chlorphentermine Hydrochloride is the hydrochloride salt form of chlorphentermine, a chlorinated analogue of phentermine, a sympathomimetic amine with central nervous system (CNS) stimulating and anorexic activity. Chlorphentermine acts by facilitating the release of catecholamines, especially noradrenaline and dopamine, from nerve terminals in the brain and also inhibits their uptake. The increase in synaptic concentrations of these catecholamines causes behavioral changes including an increase in motor activity, mental alertness and excitement, causes euphoria, and suppresses appetite.
Namen und Bezeichner
- Bevorzugter Name
- Chlorphentermine Hydrochloride
- IUPAC
- 1-(4-chlorophenyl)-2-methylpropan-2-amine;hydrochloride
- Lokaler Name
- Avicol
- Englischer Name
- chlorphentermine hydrochloride
- Summenformel
- C10H14ClN.ClH
- Molmasse
- 0
Namen und Synonyme
Chlorphentermine hydrochloride151-06-4Pre-SateLucofenChlorphentermine HClNSC-76098DTXSID1047815RL11HOJ7DMW 2426p-Chloro-alpha,alpha-dimethylphenethylamine hydrochlorideDTXCID3027792Benzeneethanamine, 4-chloro-alpha,alpha-dimethyl-, hydrochloride
Weitere Namen anzeigen
α,α-DiMeImidazo[2,1-b]oxazole,6-(5-fluorophenyl)-p-Chloro-α,α-diMethylphenethylaMine Hydrochloride4-Chloro-α,α-diMethylphenethylaMine Hydrochloride(4-Chlorophenyl)-2-Methylpropan-2-aMine Hydrochloride4-Chloro-a,a-diMethyl-benzeneethanaMine hydrochloride4-Chloro-α,α-diMethyl-1-benzeneethanaMine Hydrochloride
W-2426NSC76098RefChem:54809Hydrochloride, Chlorphentermine205-782-91-(4-chlorophenyl)-2-methylpropan-2-amine hydrochlorideDezopimonLucofene
Datenbank-Bezeichner
- CAS
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 26 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 13
- Formalladung
- 0
- Komplexität
- 137
Experimentelle und physikochemische Eigenschaften
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Physikochemische Eigenschaften
- Schmelzpunkt
- 234 ℃ · 234℃
- Löslichkeit
- 2 O: · H2O: 2 mg/mL, clear
- Aggregatzustand
- Solid
- Farbe
- white to beige
- SMILES
- NC(C)(C)CC1=CC=C(C=C1)Cl.Cl
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
P203, P264, P270, P280, P301+P316, P318, P321, P330, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory InformationBenzeneethanamine, 4-chloro-.alpha.,.alpha.-dimethyl-, hydrochloride: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and CategoriesAcute Tox. 3 (100%)
Sicherheitsdaten
- Toxizität
- LD50 in mice (mg/kg): 270 orally; 267 s.c. (Ciborska)
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters.
Anwendungen
Verwendenchlorphentermine hydrochloride is an anorectic agent. Chlorphentermine is the 4-chloro derivative of the better known appetite suppressant Phentermine (P318830). chlorphentermine hydrochloride is structurally related to amphetamine but is a relatively weak stimulant with little abuse potential.
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