Betamethasone Sodium Phosphate｜Huagongshe

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HCID 65478Erstellt: 26. Oktober 2026

Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, Dinatriumsalz, (11β,16β)-

BETAMETHASONE SODIUM PHOSPHATE · BETAMETHASONE 21-DISODIUM PHOSPHATE · Durabetason · betnesol · bentelan · BETAMETHASONE 21-PHOSPHATE DISODIUM SALT · Celestan · Bentalan

https://huagongshe.com/de/chemical/65478

Molekülstruktur von Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, Dinatriumsalz, (11β,16β)-

Identifikatoren & physikalische Daten

CAS No.	151-73-5
Summenformel	C22H28FNa2O8P
Durchschnittliche Molmasse	516,4 g/mol
Monoisotopische Masse	516,13012157 g/mol
SMILES	C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)COP(=O)([O-])[O-].[Na+].[Na+]
InChIKey	PLCQGRYPOISRTQ-LWCNAHDDSA-L
PubChem CID	65478
ChEMBL	CHEMBL1200762
ChEBI	CHEBI:3078
EC No.	205-797-0
DTXSID	DTXSID8047137
Lokaler Name	Pregna-1,4-dien-3,20-dion, 9-Fluor-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, Dinatriumsalz, (11β,16β)-

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)	147
H-Brücken-Donoren	2
H-Brücken-Akzeptoren	9
Frei drehbare Bindungen	3
Schwere Atome	34
Formalladung	0
Komplexität	961
Schmelzpunkt	206-211°C
Lagerbedingungen	room temp
Löslichkeit	Freely soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.water: 50mg/mL, clear to very slightly hazy, faintly yellow
Aggregatzustand	Solid
Farbe	White to Off-White
pH	7.5~9.0(5g/l, 25℃)
Merck	14,1180
Stabilität	Hygroscopic
InChIKey	PLCQGRYPOISRTQ-LWCNAHDDSA-L
SMILES	[C@@]12([H])C[C@H](C)[C@](O)(C(=O)COP([O-])([O-])=O)[C@@]1(C)C[C@H](O)[C@]1(F)[C@@]3(C)C=CC(=O)C=C3CC[C@@]21[H].[Na+].[Na+] \|&1:0,3,5,15,18,20,22,32,r\|
EPA chemische Informationen	.beta.-Methasone disodium phosphate (151-73-5)

Sicherheit & Vorschriften

GHS-Einstufung	DangerH302 (44.2%): Harmful if swallowed [Warning Acute toxicity, oral]H330 (54.9%): Fatal if inhaled [Danger Acute toxicity, inhalation]H360 (42.5%): May damage fertility or the unborn child [Danger Reproductive toxicity]H360D (15%): May damage the unborn child [Danger Reproductive toxicity]H372 (48.7%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]H373 (12.4%): May causes damage to organs through prolonged or repeated exposure [Warning Specific target organ toxicity, repeated exposure]H410 (46.9%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]P203, P260, P264, P270, P271, P273, P280, P284, P301+P317, P304+P340, P316, P318, P319, P320, P330, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 113 reports by companies from 13 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Regulatorische Informationen	Betamethasone sodium phosphate: Does not have an individual approval but may be used under an appropriate group standard
Weitere Sicherheitsinformationen	IMAP assessments - Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-: Environment tier I assessmentIMAP assessments - Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-: Human health tier I assessment
Hazard Classes and Categories	Acute Tox. 4 (44.2%)Acute Tox. 2 (54.9%)Repr. 1B (42.5%)Repr. 1B (15%)STOT RE 1 (48.7%)STOT RE 2 (12.4%)Aquatic Chronic 1 (46.9%)