HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat
r33800 · Sufenta · Sufentanil Forte · r30730citratesalt · sufentanylcitrate · Sufentanyl Citrat · SUFENTANIL CITRATE · SUFENTANILCITRATE,USP
![Molekülstruktur von N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat](/img/chemical/65494.png)
Identifikatoren & physikalische Daten
| CAS No. | 60561-17-3 |
|---|---|
| Summenformel | C28H38N2O9S |
| Durchschnittliche Molmasse | 578,7 g/mol |
| Monoisotopische Masse | 578,2298018 g/mol |
| SMILES | CCC(=O)N(c1ccccc1)C1(COC)CCN(CCc2cccs2)CC1.O=C(O)CC(O)(CC(=O)O)C(=O)O |
| InChIKey | OJCZPLDERGDQRJ-UHFFFAOYSA-N |
| PubChem CID | 65494 |
| ChEMBL | CHEMBL1201163 |
| ChEBI | CHEBI:9317 |
| EC No. | 262-295-4 |
| DTXSID | DTXSID5048928 |
| Lokaler Name | N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 193 |
|---|---|
| H-Brücken-Donoren | 4 |
| H-Brücken-Akzeptoren | 11 |
| Frei drehbare Bindungen | 13 |
| Schwere Atome | 40 |
| Formalladung | 0 |
| Komplexität | 687 |
| Human Drugs | FDA approved drugs -> Active ingredient |
| Schmelzpunkt | 96.60C |
| Flammpunkt | 9℃ |
| Lagerbedingungen | -20°C Freezer |
| Löslichkeit | H2O: soluble1mg/mL, clear |
| Aggregatzustand | powder |
| Farbe | white to beige |
| Stabilität | Hygroscopic |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH300+H310+H330 (90.7%): Fatal if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oralacute toxicity, dermalacute toxicity, inhalation]P260, P262, P264, P270, P271, P280, P284, P301+P316, P302+P352, P304+P340, P316, P320, P321, P330, P361+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 43 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Weitere Sicherheitsinformationen | IMAP assessments - Propanamide, N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenyl-, 2-hydroxy-1,2,3-propane tricarboxylate (1:1): Environment tier I assessment |
| Hazard Classes and Categories | Acute Tox. 2 (100%) |
| Drug Induced Liver Injury | Drug Induced Liver Injury Rank (DILIrank 2.0)Sufentanil citratevNo-DILI-concernNo matchDOI:10.1016/j.drudis.2016.02.015 |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | 3249 |
| Zollcode | 2934910000 |
| R-Sätze (R) | 26/27/28-39/23/24/25-23/24/25-11 |
| Toxizität | LD50 intravenous in dog: 14100ug/kg |
| Gefahrensymbole | T+,T,F |
| Sicherheitshinweise (S) | 26-27-28-36/37/39-45-36/37-16-7 |
| Gefahrenklasse | 6.1(b) |
| Verpackungsgruppe | III |
Anwendungen & Verwendung
Verwenden
Potent derivative of Fentanyl. Analgesic (narcotic). Controlled substance (opiate)