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4-Ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
RUBETICAN · 9-NITRO-CPT · 10-Nitro-CaMptothecin · CAMPTOTHECIN, 9-NITRO-20(S)- · 4-Ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione · 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-9-nitro- · 10-Nitrocamptothecin/4-Ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione
![Molekülstruktur von 4-Ethyl-4-hydroxy-9-nitro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione](/img/chemical/65567.png)
Identifikatoren & physikalische Daten
| CAS No. | 104195-61-1 |
|---|---|
| Summenformel | C20H15N3O6 |
| Durchschnittliche Molmasse | 393,3 g/mol |
| Monoisotopische Masse | 393,0960852 g/mol |
| SMILES | CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc([N+](=O)[O-])ccc3nc2-1 |
| InChIKey | XLHNAFUKOSPOAT-UHFFFAOYSA-N |
| PubChem CID | 65567 |
| ChEMBL | CHEMBL417730 |
| DTXSID | DTXSID10908841 |
Chemische & physikalische Eigenschaften
| XLogP | 0,8 |
|---|---|
| Polarare Oberfläche (TPSA) | 126 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 7 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 29 |
| Formalladung | 0 |
| Komplexität | 861 |
| Löslichkeit | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| Aggregatzustand | Powder |
Anwendungen & Verwendung
Verwenden
10-Nitrocamptothecin is a Camptothecin (C175150) derivative used in the treatment of cancers. Used in the treatment of hyperproliferative diseases.