HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Clobenosid
43853 · Ba43853 · Ba 43853 · Ba-43853 · clobenoside · Clobenoside, Floganol, Arvigol · Ethyl 5,6-bis-O-(p-chlorobenzyl)-3-O-propyl-D-glucofuranoside · Ethyl 5-O,6-O-bis(4-chlorobenzyl)-3-O-propyl-D-glucofuranoside
Identifikatoren & physikalische Daten
| CAS No. | 29899-95-4 |
|---|---|
| Summenformel | C25H32Cl2O6 |
| Durchschnittliche Molmasse | 499,4 g/mol |
| Monoisotopische Masse | 498,1575941 g/mol |
| SMILES | CCCO[C@H]1[C@@H]([C@@H](COCc2ccc(Cl)cc2)OCc2ccc(Cl)cc2)OC(OCC)[C@@H]1O |
| InChIKey | UOYOWSGCMGEQHC-MSEXXDKFSA-N |
| PubChem CID | 65769 |
| ChEMBL | CHEMBL3989839 |
| ChEBI | CHEBI:135801 |
| EC No. | 249-940-5 |
| DTXSID | DTXSID101043377 |
| Lokaler Name | Clobenosid |
Chemische & physikalische Eigenschaften
| XLogP | 4,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 66,4 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 13 |
| Schwere Atome | 33 |
| Formalladung | 0 |
| Komplexität | 525 |
Anwendungen & Verwendung
Beschreibung
Clobenoside is a vasoprotective agent with antiinflammatory activity. It is indicated for the topical treatment of chronic venous insufficiency and post-thrombotic syndrome. Clobenoside is also reportedly effective in treating traumatic edema through its inhibitory effects on histamine and/or kinins.