HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Eltoprazine
DU-28853 · EltoprazineHCl · Eltoprazine (DU-28853) · ELTOPRAZINE HYDROCHLORIDE · 5-Piperazino-2,3-dihydro-1,4-benzodioxin · 5-(Piperazin-1-yl)-2,3-dihydro-1,4-benzodioxin · N-(2,3-Dihydrobenzo[1,4]dioxin-5-yl)piperazine · 4(2,3-dihydro-benzo[1,4]dioxin-5-yl)-piperazine
Identifikatoren & physikalische Daten
| CAS No. | 98224-03-4 |
|---|---|
| Summenformel | C12H16N2O2 |
| Durchschnittliche Molmasse | 220,27 g/mol |
| Monoisotopische Masse | 220,12117775 g/mol |
| SMILES | c1cc2c(c(N3CCNCC3)c1)OCCO2 |
| InChIKey | WVLHGCRWEHCIOT-UHFFFAOYSA-N |
| PubChem CID | 65853 |
| ChEMBL | CHEMBL282614 |
| ChEBI | CHEBI:234413 |
| EC No. | 872-479-1 |
| DTXSID | DTXSID5048425 |
Chemische & physikalische Eigenschaften
| XLogP | 1,1 |
|---|---|
| Polarare Oberfläche (TPSA) | 33,7 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 16 |
| Formalladung | 0 |
| Komplexität | 231 |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Lagerbedingungen | Store at RT |
| Löslichkeit | DMSO : ≥ 25 mg/mL (113.50 mM) |
| Aggregatzustand | Powder |
| Farbe | White to off-white |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P280, P301+P316, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 3 (100%) |
| Alarmwort | Warnung |
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
Anwendungen & Verwendung
Verwenden
Eltoprazine is a partial agonist at SR-1 and SR-2C. Also, it is a 5-HT1A/1B receptor agonist.