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Hydroxytrimethylsilan
TMSOH · Trimethylsilanol · Silanol, trimethyl- · Trimethylhydroxysilane · DK031 · LS 310 · Silanole · 213-914-1
Identifikatoren & physikalische Daten
| CAS No. | 1066-40-6 |
|---|---|
| Summenformel | C3H10OSi |
| Durchschnittliche Molmasse | 90,2 g/mol |
| Monoisotopische Masse | 90,05009147 g/mol |
| SMILES | C[Si](C)(C)O |
| InChIKey | AAPLIUHOKVUFCC-UHFFFAOYSA-N |
| PubChem CID | 66110 |
| ChEMBL | CHEMBL4238997 |
| EC No. | 213-914-1 |
| DTXSID | DTXSID7061433 |
| Lokaler Name | Hydroxytrimethylsilan |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 20,2 |
|---|---|
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 28,4 |
| Stoffklassen | Metals -> Metalloid Compounds (Silicon) |
| SpringerMaterials Properties | 29Si nuclear magnetic resonance spectrum |
| Dampfdruck | 0.14 [mmHg]19-55hPa at 25℃ |
| Food Contact Substances | FCS -> FDA Cumulative Estimated Daily Intake (CEDI) |
| Physical Description | Colorless liquid with a strong odor[Wacker Silicones MSDS] |
| Schmelzpunkt | -4.5 °C |
| Siedepunkt | 90℃/760Torr |
| Dichte | 0.950 |
| Brechungsindex | 1.3889 |
| Flammpunkt | 4°(39°F) |
| Lagerbedingungen | Sealed in dry,Store in freezer, under -20°C |
| Löslichkeit | Chloroform (Sparingly), DMSO (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)Soluble in water (1.00 mg/ml). |
| Aggregatzustand | liquid |
| pKa (Säurekonstante) | 12.67±0.58(Predicted) |
| Wichte | 0.8139 |
| Farbe | Clear, colourless |
| BRN | 1361356 |
| Henry-Konstante | 7.0×10-2 mol/(m3Pa) at 25℃, Xu and Kropscott (2014) |
| InChI | 1S/C3H10OSi/c1-5(2,3)4/h4H,1-3H3 |
| InChIKey | AAPLIUHOKVUFCC-UHFFFAOYSA-N |
| SMILES | C[Si](C)(C)O |
| LogP (Verteilungskoeffizient) | 1.19-5.06 at 20-25℃ |
| NIST chemische Informationen | Silanol, trimethyl(1066-40-6) |
| EPA chemische Informationen | Silanol, trimethyl- (1066-40-6) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 2.2% (5 of 232) of reports.DangerH225 (97.8%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P271, P280, P303+P361+P353, P304+P340, P317, P319, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 232 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Not Classified |
|---|---|
| Regulatorische Informationen | Chemical: Silanol, trimethyl-PMN - indicates a commenced PMN (Pre-Manufacture Notices) substance.Status: Active Update: 02-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/23873Silanol, trimethyl-: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right. |
| Gefahrenübersicht | Reduced spontaneous motor activity, staggering gait, and decreased body weight observed in 28-day oral study of rats at the highest tested dose (640 mg/kg/day)No evidence of mutagenicity[JECDB] Contains 10-30% hexamethyl disiloxane (CAS# 107-46-0) as an impurityMay cause mild eye irritation[Wacker Silicones MSDS] See Hexamethyldisiloxane and Dimethylsilane. |
| Hazard Classes and Categories | Flam. Liq. 2 (97.8%)Flammable liquids - Category 2 |
| Protective Action Criteria (PAC) | 2.1 [ppm]23 [ppm]140 [ppm] |
| Unerwünschte Wirkungen | Neurotoxin - Other CNS neurotoxin |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 1993BF 3 / PGII |
Anwendungen & Verwendung
Beschreibung
Trimethylsilanol has strong acidity compared with the corresponding carbon alcohols, can react with tetrahydrolithium aluminum, Si-OH bond can be reduced Si-H bond, can be used as a blocking agent for straight-chain polysiloxanes with hydrophobicity, it is the most important intermediate in the preparation of organosilicon alcohol salts and all kinds of polysiloxanes products including silicone oils, silicone rubbers and silicone resins, etc, and it has a wide range of application prospects.
Verwenden
Trimethylsilanol used as a hydrophobic coat on silicate surfaces. Used as an as an antimicrobial agent.