Ethyl-2-hydroxy-2-methylpropionat

Ethyl 2-hydroxyisobutyrate

HCID 6653
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Grundinformationen

CAS
80-55-7
Standard-SMILES
CCOC(=O)C(C)(C)O
InChIKey
GFUIDHWFLMPAGY-UHFFFAOYSA-N
Summenformel
C6H12O3
Durchschnittliche Molmasse
132,16 g/mol
Monoisotopische Masse
132,07864424

Namen und Bezeichner

Bevorzugter Name
Ethyl 2-hydroxyisobutyrate
IUPAC
ethyl 2-hydroxy-2-methylpropanoate
Lokaler Name
Ethyl-2-hydroxy-2-methylpropionat
Englischer Name
Ethyl 2-hydroxyisobutyrate
Summenformel
C6H12O3
Molmasse
132.16

Namen und Synonyme

Ethyl 2-hydroxyisobutyrateEthyl 2-hydroxy-2-methylpropanoateEthyl 2-hydroxy-2-methylpropionateEthyl 2-methyllactateEthyl alpha-hydroxyisobutyratePropanoic acid, 2-hydroxy-2-methyl-, ethyl ester2-Methyllactic acid ethyl esterLACTIC ACID, 2-METHYL-, ETHYL ESTER2-Hydroxyisobutyric Acid Ethyl EsterEthyl .alpha.-hydroxyisobutyrateNSC 4667EINECS 201-290-3
Weitere Namen anzeigen
Ethyl α-hydroxyisobuEthyl hydroxyisobtyrateEthyl hydroxyisobutyrateEthyl α-hydroxyisobutyraEthyl α-hydroxyisobutyrateEthyl 2-hydroxyisobutanoate
UNII-S1530MCV3XBRN 0878308S1530MCV3XAI3-09122NSC-46672-hydroxy-2-methylpropionic acid ethyl esterDTXSID40738854-03-00-00783 (Beilstein Handbook Reference)

Datenbank-Bezeichner

CAS
80-55-7
PubChem CID
6653
DTXSID
DTXSID4073885
UNII
S1530MCV3X
EC Number
201-290-3
Nikkaji
J132.714C

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,4
Polarare Oberfläche (TPSA)
46,5 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
3
Frei drehbare Bindungen
3
Schwere Atome
9

Physikochemische Eigenschaften

Schmelzpunkt
78 °C · 78 °C
Siedepunkt
150 °C · 150 °C (lit.)
Dichte
0.965 g/mL · 0.965 g/mL at 25 °C (lit.)
Brechungsindex
20 · n20/D 1.408(lit.)
Flammpunkt
112 °F · 112 °F
storage temp.
Flammables area

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Warning

H226 (100%): Flammable liquid and vapor [Warning Flammable liquids]；H315 (87.2%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (95.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (93.6%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]

P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 47 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory InformationEthyl 2-methyllactate: Does not have an individual approval but may be used under an appropriate group standard
Hazard Classes and CategoriesFlam. Liq. 3 (100%)；Skin Irrit. 2 (87.2%)；Eye Irrit. 2A (95.7%)；STOT SE 3 (93.6%)

Sicherheit und Schutzausrüstung

Protective Action Criteria (PAC) · 3 Einträge

12 [mg/m3]

130 [mg/m3]

790 [mg/m3]

Regulatorische Informationen

Regulatory InformationEthyl 2-methyllactate: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

wgk
3
ridadr
UN 3272 3/PG 3
hs_code
29181980
RTECS-Nr.
OD5672000
risk_code
10-36/37/38-36/38
hazard_code
Xi

Chemie und Industrie

Anwendungen · 2 Einträge

BeschreibungEthyl 2-hydroxyisobutyrate (E-2HIBA) has a wide range of applications in flavor and fragrance ingredients, green solvents, and pharmaceuticals. E-2HIBA has been synthesized by the batch transesterification of methyl 2-hydroxyisobutyrate with ethanol in the presence of titanium tetraethoxide (reaction conditions: 96 h, yield 97 %) and the esterification of 2-HIBA with an acid catalyst. The direct esterification of 2-HIBA with ethanol using an acid catalyst appears to be a commercially viable approach to produce E-2HIBA [1].

VerwendenSolvent for nitrocellulose and cellulose acetate; solvent mixture for cellulose ethers, organic synthesis, pharmaceuticals.

Vor- und nachgelagerte Produkte

Anbieter65 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
阿诺西（上海）生物技术有限公司400-1107768 15058188853 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
Hebei Chuanghai Biotechnology Co., Ltd+86-17732866630 · [email protected]
江苏艾康生物医药研发有限公司025-025-66113011 15955137747 · [email protected]

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