HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Caramiphenhydrochlorid
G 2747 · Parpanit · Parpanil · Panparnit · PARPANIT HYDROCHLORIDE · Pentaphene hydrochloride · caramiphen hydrochloride · Caramiphenium chloride salt
Identifikatoren & physikalische Daten
| CAS No. | 125-85-9 |
|---|---|
| Summenformel | C18H28ClNO2 |
| Durchschnittliche Molmasse | 325,9 g/mol |
| Monoisotopische Masse | 325,1808568 g/mol |
| SMILES | CCN(CC)CCOC(=O)C1(c2ccccc2)CCCC1.Cl |
| InChIKey | MUPNXGNOIBYHSG-UHFFFAOYSA-N |
| PubChem CID | 67173 |
| ChEMBL | CHEMBL1598472 |
| EC No. | 204-758-5 |
| DTXSID | DTXSID70154544 |
| Lokaler Name | Caramiphenhydrochlorid |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 29,5 |
|---|---|
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 8 |
| Schwere Atome | 22 |
| Formalladung | 0 |
| Komplexität | 313 |
| Schmelzpunkt | 145-146° |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | H2O: ≥5mg/mL |
| Aggregatzustand | powder |
| Farbe | white to beige |
| InChI | 1S/C18H27NO2.ClH/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3 |
| InChIKey | MUPNXGNOIBYHSG-UHFFFAOYSA-N |
| SMILES | Cl.CCN(CC)CCOC(=O)C1(CCCC1)c2ccccc2 |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| R-Sätze (R) | 22 |
| Toxizität | LD50 i.p. in rats: 209 mg/kg (Kraatz) |
| Gefahrensymbole | Xn |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Acute Tox. 4 Oral |
Anwendungen & Verwendung
Verwenden
Caramiphen hydrochloride has been used to test its inhibitory effect on voltage-gated Na+ currents using the patch-clamp method.