HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Mafenidhydrochlorid
MAFENIDE · masudin · morfanil · MARFANIL · MAFENIDEHCL · LABOTEST-BB LT00454465 · LABOTEST-BB LTBB000725 · MAFENIDE HYDROCHLORIDE
Identifikatoren & physikalische Daten
| CAS No. | 138-37-4 |
|---|---|
| Summenformel | C7H11ClN2O2S |
| Durchschnittliche Molmasse | 222,69 g/mol |
| Monoisotopische Masse | 222,02297627 g/mol |
| SMILES | Cl.NCc1ccc(S(N)(=O)=O)cc1 |
| InChIKey | SIACJRVYIPXFKS-UHFFFAOYSA-N |
| PubChem CID | 67313 |
| ChEMBL | CHEMBL1593568 |
| EC No. | 205-325-3 |
| DTXSID | DTXSID6045296 |
| Lokaler Name | Mafenidhydrochlorid |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 94,6 |
|---|---|
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 224 |
| Arzneimittel | Pharmaceuticals -> Antibiotics |
| Schmelzpunkt | 261-263 °C(lit.) |
| Lagerbedingungen | Inert atmosphere,Room Temperature |
| Löslichkeit | DMSO (Slightly), Methanol (Slightly) |
| Aggregatzustand | Solid |
| Farbe | White |
| Merck | 13,5671 |
| Hauptanwendungen | forensics and toxicologypharmaceutical (small molecule) |
| Kosmetik-Inhaltsstoffe Funktionen | ANTIMICROBIAL |
| InChI | InChI=1S/C7H10N2O2S.ClH/c8-5-6-1-3-7(4-2-6)12(9,10)11/h1-4H,5,8H2,(H2,9,10,11)1H |
| InChIKey | SIACJRVYIPXFKS-UHFFFAOYSA-N |
| SMILES | C1(S(=O)(=O)N)=CC=C(CN)C=C1.Cl |
| CAS Datenbank | 138-37-4(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Skin Sens. 1 (100%) |
| Wassergefährdungsklasse (WGK) | 2 |
| Zollcode | 29350090 |
| RTECS-Nr. | XT5425000 |
| R-Sätze (R) | 42/43 |
| Toxizität | LD50 in rats, mice (mg/kg): 1170, 900 i.v. (Skulan, Hoppe) |
| Gefahrensymbole | Xn |
| Sicherheitshinweise (S) | 22-36/37-45 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Skin Sens. 1 |
Anwendungen & Verwendung
Verwenden
Antibacterial;Inhibitor of folic acid biosynthesis