2,2-Difluorobenzo[d][1,3]dioxol-5-ol

2,2-difluorobenzo[d][1,3]dioxol-5-ol · 2,2-Difluorobenzodioxol-5-ol · 2,2-Difluoro-1,3-benzodioxol-5-ol · 1,3-Benzodioxol-5-ol, 2,2-difluoro-

https://huagongshe.com/de/chemical/67356342

Molekülstruktur von 2,2-Difluorobenzo[d][1,3]dioxol-5-ol

Identifikatoren & physikalische Daten

CAS No.	1211539-82-0
Summenformel	C7H4F2O3
Durchschnittliche Molmasse	174,1 g/mol
Monoisotopische Masse	174,01285031 g/mol
SMILES	Oc1ccc2c(c1)OC(F)(F)O2
InChIKey	GEHVTOIGEVNIEQ-UHFFFAOYSA-N
PubChem CID	67356342
EC No.	828-148-9

Chemische & physikalische Eigenschaften

XLogP	2,1
Polarare Oberfläche (TPSA)	38,7
H-Brücken-Donoren	1
H-Brücken-Akzeptoren	5
Frei drehbare Bindungen	0
Schwere Atome	12
Formalladung	0
Komplexität	185
Lagerbedingungen	under inert gas (nitrogen or Argon) at 2-8°C
Aggregatzustand	solid
Farbe	White to off-white

Sicherheit & Vorschriften

GHS-Einstufung	WarningH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (50%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (50%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 2 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Hazard Classes and Categories	Acute Tox. 4 (100%)Skin Irrit. 2 (50%)Eye Irrit. 2A (50%)STOT SE 3 (50%)
Zollcode	2932990090

Anwendungen & Verwendung

Verwenden

2,2-Difluorobenzodioxol-5-ol is used in the preparation of isobenzofuro[6,5-f][1,3]benzodioxolones as small molecule inhibitor of insulin-like growth factor-1 receptor.