2,8-Dichloroquinoline
Grundinformationen
- CAS
4470-83-1- Standard-SMILES
Clc1ccc2cccc(Cl)c2n1- InChIKey
VAXOCTXTVIVOQE-UHFFFAOYSA-N- Summenformel
- C9H5Cl2N
- Durchschnittliche Molmasse
- 198,05 g/mol
- Monoisotopische Masse
- 196,9799046
Namen und Bezeichner
- Bevorzugter Name
- 2,8-Dichloroquinoline
- IUPAC
- 2,8-dichloroquinoline
- Englischer Name
- 2,8-DICHLOROQUINOLINE
- Summenformel
- C9H5Cl2N
- Molmasse
- 198.05
Namen und Synonyme
2,8-Dichloroquinoline4470-83-1DTXSID60350316RefChem:248962DTXCID80301385627-428-6Quinoline, 2,8-dichloro-MFCD008320772,8-dichloro-quinolineSCHEMBL8450372,8-Dichloroquinoline, 96%AS-18366
Weitere Namen anzeigen
Obefazimod(ABX-464)2,8-Dichloroquinoline 96%2,8-DICHLOROQUINOLINE ISO 9001：2015 REACH
SY013566EN300-128589F0001-2437AMY38314BCP28043VAXOCTXTVIVOQFT-0635317A846621
Datenbank-Bezeichner
- CAS
4470-83-1- PubChem CID
- 676553
- DTXSID
DTXSID60350316- EC Number
- 627-428-6
- Nikkaji
- J2.226.049I
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 3,8
- Polarare Oberfläche (TPSA)
- 12,9 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 12
- Formalladung
- 0
- Komplexität
- 163
Physikochemische Eigenschaften
- Schmelzpunkt
- 105 · 105-108 °C (lit.)
- Siedepunkt
- 292.8 · 292.8±20.0 °C(Predicted)
- Dichte
- 1.407 · 1.407±0.06 g/cm3(Predicted)
- storage temp.
- 2 · under inert gas (nitrogen or Argon) at 2-8°C
- pka
- -2.33 · -2.33±0.50(Predicted)
- InChI
- InChI=1S/C9H5Cl2N/c10-7-3-1-2-6-4-5-8(11)12-9(6)7/h1-5H
- InChIKey
- VAXOCTXTVIVOQE-UHFFFAOYSA-N
- SMILES
- N1C2C(=CC=CC=2Cl)C=CC=1Cl
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 2.3% (1 of 43) of reports.
Warning
H315 (97.7%): Causes skin irritation [Warning Skin corrosion/irritation]；H319 (97.7%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (97.7%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 43 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Reported as not meeting GHS hazard criteria per 1 of 43 reports by companies.；There are 5 notifications provided by 42 of 43 reports by companies with hazard statement code(s).；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Gefahrenhinweise
Regulatory InformationStatus: Active Update: 21-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/32991
Hazard Classes and CategoriesSkin Irrit. 2 (97.7%)；Eye Irrit. 2 (97.7%)；STOT SE 3 (97.7%)
Regulatorische Informationen
Regulatory InformationStatus: Active Update: 21-09-2021 https://echa.europa.eu/registration-dossier/-/registered-dossier/32991
Chemie und Industrie
Anwendungen
Verwenden2,8-Dichloroquinoline may be used in the neat synthesis of 8-chloro-2-(thiophen-2-ylsulfanyl)quinolone. It may also be used in the preparation of 2-methyl-4-[-2′-(8′-chloroquinolyl)]-but-3-yn-2-ol.
Vor- und nachgelagerte Produkte
Nachgelagerte Produkte
Anbieter100 Anbieter
河北凡博医药科技有限公司15588346797 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
Suzhou Victorypharm Co.,Ltd.+86-13916956214 · [email protected]
环生美森医药技术（山东）有限公司0531-88762217 18301471076 · [email protected]
宁波季诺化学品有限公司0574-87314919 057487319282 · [email protected]
上海瀚麟生物科技有限公司183-0212-4410 18302124410 · [email protected]
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
郑州鸿晟医药科技有限公司0371-55695890 15637198702 · [email protected]
Zugehörige Reaktionen
7
Notizen zur Verbindung
Wird geladen…