HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Fluorpyridin
250 · 3-FLUOROPYRIDINE · 3-Floro-pyridine · 3-Fluoroypyridine · 3-Fluoropyridine>Pyridine, 3-fluoro- · 3-Fluoropyridine 98% · 3-Fluoropyridine,98% · 3-Fluoropyridine,99%
Identifikatoren & physikalische Daten
| CAS No. | 372-47-4 |
|---|---|
| Summenformel | C5H4FN |
| Durchschnittliche Molmasse | 97,09 g/mol |
| Monoisotopische Masse | 97,03277735 g/mol |
| SMILES | Fc1cccnc1 |
| InChIKey | CELKOWQJPVJKIL-UHFFFAOYSA-N |
| PubChem CID | 67794 |
| ChEMBL | CHEMBL1162361 |
| EC No. | 206-755-4 |
| DTXSID | DTXSID10190688 |
| Lokaler Name | 3-Fluorpyridin |
Chemische & physikalische Eigenschaften
| XLogP | 0,8 |
|---|---|
| Polarare Oberfläche (TPSA) | 12,9 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 7 |
| Formalladung | 0 |
| Komplexität | 56 |
| SpringerMaterials Properties | Coriolis coupling |
| Schmelzpunkt | 251-254°C (dec.) |
| Siedepunkt | 107-108 °C (lit.) |
| Dichte | 1.13 g/mL at 25 °C (lit.) |
| Brechungsindex | n20/D 1.472(lit.) |
| Flammpunkt | 56 °F |
| Lagerbedingungen | Inert atmosphere,Room Temperature |
| Aggregatzustand | Liquid |
| pKa (Säurekonstante) | pK1:2.97(+1) (25°C) |
| Wichte | 1.130 |
| Farbe | Clear yellow |
| BRN | 105702 |
| InChI | InChI=1S/C5H4FN/c6-5-2-1-3-7-4-5/h1-4H |
| InChIKey | CELKOWQJPVJKIL-UHFFFAOYSA-N |
| SMILES | C1=NC=CC=C1F |
| CAS Datenbank | 372-47-4(CAS DataBase Reference) |
| NIST chemische Informationen | 3-F-pyridine(372-47-4) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P271, P280, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 61 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Flam. Liq. 2 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | UN 1993 3/PG 2 |
| Zollcode | 29333990 |
| R-Sätze (R) | 11-36/37/38-20/21/22 |
| Gefahrensymbole | F,Xi,Xn |
| hazard_note | Flammable/Irritant |
| Sicherheitshinweise (S) | 16-26-36/37/39-33-7/9 |
| Gefahrenklasse | 3Eye Irrit. 2Flam. Liq. 2Skin Irrit. 2STOT SE 3 |
| Verpackungsgruppe | II |
| Lagerklasse | 3 - Flammable liquids |
Anwendungen & Verwendung
Verwenden
3-Fluoropyridine was used in the synthesis of 3-halopyridin-4-yl-boronic acids and esters.
Herstellung & Synthese
synthetische
A combination of CsF and HF provides a very reactive fluoride source and has shown faint promise with 3-chloropyridine giving 3-fluoropyridine in a very low yield.