| GHS-Einstufung | DangerH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P284, P301+P317, P302+P352, P304+P340, P305+P351+P338, P316, P319, P320, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 28 reports by companies from 1 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
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| Regulatorische Informationen | Hazard Traits - Developmental ToxicityOcular ToxicityRegulation (EC) No 396/2005 (amended)01/21/EC, 2010/77/EU, Reg. (EU) 2015/1885, Reg. (EU) 2016/549, Reg. (EU) 2017/841, Reg. (EU) 2018/1532, Reg. (EU) 2018/917, Reg. (EU) No 540/2011Diquat: HSNO Approval: HSR006720 Approved with controls |
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| DOT-Kennzeichnung | Poison |
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| Brandgefahren | Behavior in Fire: Decomposes at high temperature, charring rather than melting or boiling. (USCG, 1999) |
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| Gesundheitsgefahren | INHALATION: No appreciable vapor pressure. Prolonged contact with spray or mist may cause oral and nasal irritation. EYES: Irritation. SKIN: Irritation. INGESTION: Vomiting, diarrhea, general malaise. Possible kidney and liver damage, dyspnea, and pulmonary edema. With large doses there may be tremors or convulsions. OTHER: May be fatal if swallowed, inhaled, or absorbed through skin. (USCG, 1999) |
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| Gefahrenübersicht | Poisoning usually occurs after toxic ingestion, e.g., attempted suicide. Symptoms of poisoning include acute renal failure, shock, convulsions, delirium, and skin burns. Diquat does not cause progressive pulmonary fibrosis as seen after paraquat poisoning. [EPA Pesticides, p. 111] Among the many herbicides in use, only the bipyridyl compounds have appeared to produce hepatic injury in humans. Even these agents have produced hepatic injury only as the result of ingestion of large amounts, not because of environmental contamination and questionably as the result of occupational exposures. [Zimmerman, p. 415] |
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| Reaktive Gruppe | Hydrocarbons, Aromatic |
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| Reactivity Profile | DIQUAT is light sensitive. This compound can corrode aluminum and other metals. (NTP, 1992) |
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| Air and Water Reactions | Water soluble. Solutions are stable in neutral and acid solutionshowever, they are unstable in alkaline solutions. |
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| Hazard Classes and Categories | Acute Tox. 4 (100%) |
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| Brandbekämpfung | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
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| Erste Hilfe | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
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| Freisetung ohne Brand | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
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| Isolation and Evacuation | Excerpt from ERG Guide 151 [Substances - Toxic (Non-Combustible)]: |
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| Threshold Limit Values (TLV) | 0.5 [mg/m3](inhalable fraction), 0.1 mg/m3(respirable fraction)0.5 mg/m³ (inhalable fraction), 0.1 mg/m³ (respirable fraction) [1990] |
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| Recommended Exposure Limit (REL) | 0.5 mg/m³ |
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| Personal Protective Equipment (PPE) | Wear face shield, rubber gloves, rubber apron when handling concentrate. When spraying, wear waterproof foot wear and clothing. (USCG, 1999) |
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| Zielorgane | Ocular |
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| Unerwünschte Wirkungen | Occupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation. |
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| Acute Toxicity Link | Chemical: DIQUAT |
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| EPA IRIS Information | DiquatOcular2.2 x 10 ^-3 mg/kg-day |
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| RAIS Toxicity Values | 0.0022IRIS Current |
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| Hazard Quotient Level 0.1 or Cancer Risk Level 1E-06 | 1.40e+021.80e+034.00e+012.00e+013.30e-011.70e-01 |
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| Hazard Quotient Level 3 or Cancer Risk Level 1E-04 | 4.20e+025.40e+031.20e+022.00e+012.20e-03Volatile |
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| UN-Transportnummer | UN2781 |
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