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Hydrocortisone aceponate
hydrocortisone aceponate · Methylprednisolone Impurity 45 · Hydrocortisone 17-Propionate 21-Acetate · [(8S,9S,10R,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-11-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] propanoate · Efficort · Suniderma · Hydrocortisonepropylacetate · Hydrocortisone 17-propionate 21-acetate in Acetonitrile
Identifikatoren & physikalische Daten
| CAS No. | 74050-20-7 |
|---|---|
| Summenformel | C26H36O7 |
| Durchschnittliche Molmasse | 460,56 g/mol |
| SMILES | CCC(=O)O[C@]1(C(=O)COC(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C |
| PubChem CID | 68921 |
| ChEMBL | CHEMBL2106309 |
| ChEBI | CHEBI:135746 |
| EC No. | 658-089-2 |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 144-146°C |
|---|---|
| Dichte | 1.23±0.1 g/cm3 (20 ºC 760 Torr) |
| Lagerbedingungen | Refrigerator |
| Löslichkeit | Chloroform (Slightly), Methanol (Slightly) |
| Aggregatzustand | Solid |
| Farbe | White to Pale Beige |
| InChIKey | MFBMYAOAMQLLPK-VRVFYZPPNA-N |
| SMILES | [C@@]1(OC(=O)CC)(C(=O)COC(=O)C)CC[C@@]2([H])[C@]3([H])CCC4=CC(=O)CC[C@]4(C)[C@@]3([H])[C@@H](O)C[C@]12C |&1:0,15,17,27,29,31,34,r| |
Sicherheit & Vorschriften
| Alarmwort | Achtung |
|---|---|
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H360 |
Anwendungen & Verwendung
Beschreibung
Hydrocortisone aceponate is the 17-a-propionate derivative of hydrocortisone-21-acetate. Its is reportedly significantly superior to the latter in the treatment of dermatoses of varying severity.