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HCID 6907Erstellt: 4. November 2026

1,2,3,4,5-Pentabrom-6-chlorcyclohexan

FR-651A · chloropentabromocyclohexane · FR-651A @100 μg/mL in Toluene · 1,2,3,4-pentabromo-6-chlorocyclohexane · 1,2,3,4,5-pentabromo-6-chlorocyclohexane · 1,2,3,4,5-pentabromo-6-chloro-cyclohexan · 1-chloro-2,3,4,5,6-pentabromo-cyclohexan · 1,2,3,4,5-pentabromo-6-chlorocyclohexane.

https://huagongshe.com/de/chemical/6907

Molekülstruktur von 1,2,3,4,5-Pentabrom-6-chlorcyclohexan

Identifikatoren & physikalische Daten

CAS No.87-84-3
SummenformelC6H6Br5Cl
Durchschnittliche Molmasse513,08 g/mol
Monoisotopische Masse507,60749 g/mol
SMILESClC1C(Br)C(Br)C(Br)C(Br)C1Br
InChIKeyUZOSVZSBPTTWIG-UHFFFAOYSA-N
PubChem CID6907
EC No.201-776-5
DTXSIDDTXSID4025828
Lokaler Name1,2,3,4,5-Pentabrom-6-chlorcyclohexan

Chemische & physikalische Eigenschaften

XLogP4,4
Polarare Oberfläche (TPSA)0
H-Brücken-Donoren0
H-Brücken-Akzeptoren0
Frei drehbare Bindungen0
Schwere Atome12
Formalladung0
Komplexität150
StoffklassenOther Classes -> Halogenated Cyclic Hydrocarbons
Löslichkeitless than 0.1 mg/mL at 64 °F (NTP, 1992)
Schmelzpunkt374 to 388 °F (NTP, 1992)
Dampfdruck0.00000346 [mmHg]
Physical DescriptionPentabromochlorocyclohexane is a white solid. (NTP, 1992)[CAMEO]
Siedepunkt34.6°C (rough estimate)
Dichte5.2412 (rough estimate)
Brechungsindex1.5100 (estimate)
Henry-Konstante1.0×101 mol/(m3Pa) at 25℃, Zhang et al. (2010)
EPA chemische Informationen1,2,3,4,5-Pentabromo-6-chlorocyclohexane (87-84-3)

Sicherheit & Vorschriften

Regulatorische InformationenChemical: Cyclohexane, 1,2,3,4,5-pentabromo-6-chloro-TP - indicates a substance that is the subject of a proposed TSCA section 4 test rule.
DOT-KennzeichnungPoison
BrandgefahrenFlash point data for this chemical are not availablehowever, it is probably nonflammable. (NTP, 1992)
GesundheitsgefahrenExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:
GefahrenübersichtEffects in two year feeding study with rats include decreased body weight, increased bromine levels in tissue, and histopathological changes to colonNo other significant adverse findings in mortality, clinical, hematologic, or urinary chemistry, necropsy, or histopathology[HSDB] Effects in high-dose animal studies include colon tumors, changes in liver and bladder weight, impaired liver function, and changes in tubules and glomeruli[RTECS]
Reaktive GruppeHalogenated Organic Compounds
Reactivity ProfileHalogenated aliphatic compounds, such as PENTABROMOCHLOROCYCLOHEXANE, are moderately or very reactive. Halogenated organics generally become less reactive as more of their hydrogen atoms are replaced with halogen atoms. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
Air and Water ReactionsInsoluble in water.
BrandbekämpfungFires involving this compound may be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Erste HilfeEYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Anwendungen & Verwendung

Verwenden

1,2,3,4,5-Pentabromo-6-chlorocyclohexane is a fireproofing agent. A halogenated flame retardant.

Freisetung ohne BrandSMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then dampen the solid spill material with toluene, then transfer the dampened material to a suitable container. Use absorbent paper dampened with toluene to pick up any remaining material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent-wash all contaminated surfaces with toluene followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Isolation and EvacuationExcerpt from ERG Guide 154 [Substances - Toxic and/or Corrosive (Non-Combustible)]:
Personal Protective Equipment (PPE)RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)
Unerwünschte WirkungenOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
TSCA Test SubmissionsChronic toxicity and oncogenicity were evaluated in Fischer 344 rats (86/sex/control group, 50/sex/treated group) orally exposed to 1,2,3,4,5-pentabromo - 6-chlorocyclohexane (PBCC) in the diet for 2 years at 0, 1, 20 and 70 mg/kg/day for females and at 0, 1, 15 and 50 mg/kg/day for males based on the differential toxicity of PBCC to males and females in previous studies. There were significant differences between treated animals and controls in the following: body weights (decreased for both sexes at high-dose levels), and tissue bromine level (increased to plateau at mid- and high-dose levels in liver, fat and serum in approximately equal concentrations). There were significant increases observed in the necropsy histopathology of the colon of high-dose animals of both sexes: hemorrhage, fluid ingesta and mass or polyp formationspolyploid formations, dilatation, hypercellularity and aggregates of cellular debris in intestinal crypts, and primary polyploid adenoma or carcinoma. There were no significant differences between treated animals and controls in the following: palpable masses, mortality, clinical chemistry, hematology, urinalysis, organ weights, or necropsy and histopathology (except for that of the colon).The distribution of alpha-1,2,3,4,5-pentabromo - 6-chlorocyclohexane (PBCC) as measured by the total bromine content in adipose, liver and kidney tissues was evaluated in male and female CDF Fischer 344 rats (10/sex/group) fed PBCC at concentrations of 0 or 600 mg/kg/day in Purina Laboratory Chow for 91 days. Statistically significant increases in bromine levels were observed in all analyzed tissues of all treated animals (P < 0.05, Dunnett's test) relative to control animals. The bromine levels (ug/g) in the adipose, liver and kidney tissues of male animals (treated/control) were: 93/2.3, 413/3.9 and 810/7.7, respectivelyand of female animals: 117/2.4, 429/5.9 and 750/9.4, respectively. The total bromine in these tissues accounted for approximately 2% of the PBCC ingested during the 13 week exposure period. The biological half-life could not be determined from the data obtained from the tests.
RAIS Toxicity Values0.02SCREEN CurrentPPRTV Current
EPA Provisional Peer-Reviewed Toxicity Values1,2,3,4,5Pentabromo-6-ChlorocyclohexanePDF DocumentSuggestive evidence of carcinogenic potential2016
Hazard Quotient Level 0.1 or Cancer Risk Level 1E-062.70e+011.10e+022.80e+002.00e+021.60e-022.00e-02
Hazard Quotient Level 3 or Cancer Risk Level 1E-042.70e+031.10e+042.80e+022.00e+022.00e-02
TSCA-Inventar-StatusTSCA listed
Gefahrstoffdaten87-84-3(Hazardous Substances Data)