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Grundinformationen
- CAS
673-06-3- Standard-SMILES
[NH3+][C@H](Cc1ccccc1)C(=O)[O-]- InChIKey
COLNVLDHVKWLRT-MRVPVSSYSA-N- Summenformel
- C9H11NO2
- Durchschnittliche Molmasse
- 165,19 g/mol
Namen und Bezeichner
- Bevorzugter Name
- D-Phenylalanine
- Lokaler Name
- D-Phenylalanin
- Englischer Name
- D-Phenylalanine
- Summenformel
- C9H11NO2
- Molmasse
- 165.19
Namen und Synonyme
PHENYLALANINEd-pheH-D-PHE-OHD-Phe-OHEndorphenylD-Phenylalanin(R)-PHENYLALANINED(+)-PHENYLALANINE(R)-2-amino-3-phenylpropanoic acid(2R)-2-Amino-3-phenylpropanoic acid
Datenbank-Bezeichner
- CAS
673-06-3- PubChem CID
- 6919011
- ChEBI
CHEBI:57981
Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 273 · 273-276 °C(lit.)
- Siedepunkt
- 293.03 °C · 293.03°C (rough estimate)
- Dichte
- 1.1603 · 1.1603 (rough estimate)
- Brechungsindex
- 34 ° · 34 ° (C=2, H2O)
- storage temp.
- Store at RT.
- Löslichkeit
- Methanol (Slightly), Water (Slightly)
- Aggregatzustand
- Powder
- pka
- 2.2 · 2.2(at 25℃)
- Farbe
- White to off-white
- Wasserlöslichkeit
- 27 g/L · 27 g/L (20 ºC)
- Merck
- 14 · 14,7271
- BRN
- 2804068 · 2804068
- Stabilität
- Stable. Incompatible with strong oxidizing agents, acids, bases.
- Major Application
- cell analysis
- InChI
- 1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m1/s1
- InChIKey
- COLNVLDHVKWLRT-MRVPVSSYSA-N
- SMILES
- N[C@H](Cc1ccccc1)C(O)=O
- LogP
- 0.235 · 0.235 (est)
- CAS Datenbank
- 673 · 673-06-3(CAS DataBase Reference)
- EPA chemische Informationen
- D-Phenylalanine (673-06-3)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 29224995
- RTECS-Nr.
- AY7533000
- risk_code
- 34
- Toxizität
- TDLo orl-hmn: 500 mg/kg/5W-I:GIT JACTDZ 1(3),124,82
- hazard_code
- Xi,C
- hazard_note
- Irritant
- safety_code
- 24/25-45-36/37/39-27-26
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Anwendungen
BeschreibungD-Phenylalanine, also known as D-alpha-Amino-beta-phenylpropionic acid, is a kind of non-proteinogenic amino acid. The biological function of D-phenylalanine remains unclear. However, it has certain anti-depressant, analgesic activities and pharmacological activity at niacin receptor II. The mechanism action of its analgesic activity seems to originate from its inhibition of enkephalin degradation by the carboxypeptidase A. Enkephalins are part of your body’s natural pain relief system. When they are broken down by enkephalinase, this contributes to the sensation of pain. D-Phenylalanine is specifically thought to be beneficial for reducing feelings of chronic pain. D-phenylalanine has been used with mixed results to treat chronic pain, including pain caused by rheumatoid arthritis. The primary use of D-phenylalanine as a health supplement is the relief of discomfort.
VerwendenD-Phenylalanine, the stereoisomer of L-Phenylalanine (P319415) has been used in the synthesis of Schaeffer’s acid analogues as important structures in tuberculostatic design. They exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.
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