Glycerintridecanoat
TRYGLICERIDE · TRIDECANOIN · GLYCERYL TRIDECANOATE · Glycerol tricaprate · Glyceryl tricaprinate · Capric acid triglyceride · CAPRIN · ricaprin
Identifikatoren & physikalische Daten
| CAS No. | 621-71-6 |
|---|---|
| Summenformel | C33H62O6 |
| Durchschnittliche Molmasse | 554,8 g/mol |
| Monoisotopische Masse | 554,4546397 g/mol |
| SMILES | CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)CCCCCCCCC |
| InChIKey | LADGBHLMCUINGV-UHFFFAOYSA-N |
| PubChem CID | 69310 |
| ChEBI | CHEBI:77388 |
| EC No. | 210-702-0 |
| DTXSID | DTXSID1042651 |
| Lokaler Name | Glycerintridecanoat |
Chemische & physikalische Eigenschaften
| XLogP | 12,2 |
|---|---|
| Polarare Oberfläche (TPSA) | 78,9 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 32 |
| Schwere Atome | 39 |
| Formalladung | 0 |
| Komplexität | 543 |
| Lipide | Lipids -> Glycerolipids [GL] -> Triradylglycerols [GL03] -> Triacylglycerols [GL0301] |
| Kosmetika | Cosmetic ingredients (Tricaprin) -> CIR (Cosmetic Ingredient Review)Personal care product -> emollientSkin conditioningSolvent |
| Physical Description | Solid |
| Schmelzpunkt | 31-32 °C |
| Siedepunkt | 254 °C / 5mmHg |
| Dichte | approximate 0.98 g/ml (20℃) |
| Brechungsindex | approximate 1.44 |
| Flammpunkt | 20 °C |
| Lagerbedingungen | -20°C |
| Löslichkeit | Chloroform (Sparingly), DMSO (Slightly, Sonicated) |
| Aggregatzustand | Solid |
| Farbe | White to Off-White |
| BRN | 1717683 |
| Kosmetik-Inhaltsstoffe Funktionen | SKIN CONDITIONINGFRAGRANCEPERFUMING |
| InChI | 1S/C33H62O6/c1-4-7-10-13-16-19-22-25-31(34)37-28-30(39-33(36)27-24-21-18-15-12-9-6-3)29-38-32(35)26-23-20-17-14-11-8-5-2/h30H,4-29H2,1-3H3 |
| InChIKey | LADGBHLMCUINGV-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCC(=O)OCC(COC(=O)CCCCCCCCC)OC(=O)CCCCCCCCC |
| LogP (Verteilungskoeffizient) | 12.444 (est) |
| CAS Datenbank | 621-71-6(CAS DataBase Reference) |
| EPA chemische Informationen | Glycerol tridecanoate (621-71-6) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 100% (8 of 8) of all reports.Not ClassifiedAggregated GHS information provided per 8 reports by companies from 1 notifications to the ECHA C&L Inventory. |
|---|---|
| Regulatorische Informationen | Chemical: Decanoic acid, 1,2,3-propanetriyl esterDecanoic acid, 1,2,3-propanetriyl ester: Does not have an individual approval but may be used under an appropriate group standard |
| Weitere Sicherheitsinformationen | IMAP assessments - Decanoic acid, 1,2,3-propanetriyl ester: Human health tier I assessment |
| Hazard Classes and Categories | Not Classified |
| Toxizitätsübersicht | Safe in the present practices of use and concentration. Ingredient, concentration, and use information are available in documents discoverable at https://cir-reports.cir-safety.org |
| Wassergefährdungsklasse (WGK) | - |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 1282 3/PG 2 |
| Zollcode | 29171900 |
| RTECS-Nr. | HE0100000 |
| R-Sätze (R) | 11-20/21/22 |
| Gefahrensymbole | F,Xn |
| Sicherheitshinweise (S) | 26-28 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Beschreibung
1,2,3-Tridecanoyl glycerol is a triacylglycerol that contains decanoic acid at the sn-1, sn-2, and sn-3 positions. It has been found in human breast milk. 1,2,3-Tridecanoyl glycerol has been used as a standard for the quantification of triacylglycerols in fish oils by RP-HPLC. Formulations containing 1,2,3-tridecanoyl glycerol have been used in cosmetic products as thickening and skin-conditioning agents.
Verwenden
Tricaprin is used to construct solid lipid nanoparticles (SLNs) as delivery system for bromocriptine (B682600, Mesylate salt). It is also used in cationic SLNs to enhance p53 tumor suppressor gene transfer to lung cancer cells.