HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
10-(Chloracetyl)-10H-phenothiazin
NSC71676 · NSC239984 · SBB009876 · ZINC00507778 · NCIOpen2_003762 · EINECS 212-326-2 · 10-(Chloroacetyl)phenothiazine · 2-Chloro-1-phenothiazin-10-yl-ethanone
Identifikatoren & physikalische Daten
| CAS No. | 786-50-5 |
|---|---|
| Summenformel | C14H10ClNOS |
| Durchschnittliche Molmasse | 275,8 g/mol |
| Monoisotopische Masse | 275,0171628 g/mol |
| SMILES | O=C(CCl)N1c2ccccc2Sc2ccccc21 |
| InChIKey | NVRFGQJNKQLUPU-UHFFFAOYSA-N |
| PubChem CID | 69920 |
| ChEMBL | CHEMBL1651446 |
| EC No. | 212-326-2 |
| DTXSID | DTXSID00229198 |
| Lokaler Name | 10-(Chloracetyl)-10H-phenothiazin |
Chemische & physikalische Eigenschaften
| XLogP | 3,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 45,6 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 18 |
| Formalladung | 0 |
| Komplexität | 303 |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (100%) |
| Alarmwort | Achtung |
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
Anwendungen & Verwendung
Verwenden
10-(Chloroacetyl)-10H-phenothiazine is useful in the synthesis of phenstatin analogues which exhibits anti-proliferative activity and interaction with tubulin.