(2R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(methylsulfanyl)butanoic acid
Grundinformationen
- CAS
112883-40-6- Standard-SMILES
CSCC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O- InChIKey
BUBGAUHBELNDEW-GOSISDBHSA-N- Summenformel
- C20H21NO4S
- Durchschnittliche Molmasse
- 371,5 g/mol
- Monoisotopische Masse
- 371,11912915
Namen und Bezeichner
- Bevorzugter Name
- (2R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(methylsulfanyl)butanoic acid
- IUPAC
- (2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanylbutanoic acid
- Englischer Name
- Fmoc-Met-OH
- Summenformel
- C20H21NO4S
- Molmasse
- 371.45
Namen und Synonyme
D-FMOC-methionine(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(methylsulfanyl)butanoic acid(2R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(methylsulfanyl)butanoic acid(2R)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-4-(methylsulfanyl)butanoic acidRefChem:396899958-460-1Fmoc-D-Met-OH112883-40-6Fmoc-D-methionineN-Fmoc-D-methionineMFCD00062958(((9H-Fluoren-9-yl)methoxy)carbonyl)-D-methionine
Weitere Namen anzeigen
FMOC-D-METFmoc-Met-OHFmoc-D-Met-OH 98%Fmoc-D-methionine99%Fmoc-Met-OH USP/EP/BP
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanylbutanoic acidD-Methionine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-DTXSID90426316CS-W009765AC-17108M033692-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanyl-butyric acid
Datenbank-Bezeichner
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 3,7
- Polarare Oberfläche (TPSA)
- 101 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 5
- Frei drehbare Bindungen
- 8
- Schwere Atome
- 26
- Formalladung
- 0
- Komplexität
- 478
Physikochemische Eigenschaften
- Schmelzpunkt
- 132 °C · 132 °C
- Siedepunkt
- 614.6 · 614.6±55.0 °C(Predicted)
- Dichte
- 1.282 · 1.282±0.06 g/cm3(Predicted)
- Brechungsindex
- 30 ° · 30 ° (C=1, DMF)
- storage temp.
- 2 · 2-8°C
- Löslichkeit
- Chloroform (Slightly), DMF (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 3.72 · 3.72±0.10(Predicted)
- Farbe
- White to Off-White
- BRN
- 5384578 · 5384578
- Major Application
- peptide synthesis
- InChI
- 1S/C20H21NO4S/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m1/s1
- InChIKey
- BUBGAUHBELNDEW-GOSISDBHSA-N
- SMILES
- CSCC[C@@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
- CAS Datenbank
- 112883 · 112883-40-6(CAS DataBase Reference)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Hazard Classes and CategoriesSkin Irrit. 2 (100%)
Sicherheitsdaten
- wgk
- 3
- hs_code
- 29309090
- safety_code
- 22-24/25
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Anwendungen
VerwendenN-Fmoc-D-methionine is an N-Fmoc-protected form of D-Methionine (M260550). D-Methionine is an isomer of L-Methionine (M260440), and is known to be a cytoprotectant against Cisplatin (C499500), an anticancer agent. D-Methionine is also used to prevent noise- and drug-induced hearing loss, as well as hair loss (all of which may also be caused by Cisplatin or aminoglycosides).
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Hangzhou Go Top Peptide Biotech0571-88211921 · [email protected]
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上海弘顺生物科技有限公司15901914505 · [email protected]
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