HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Fmoc-D-Asn-OH
FMOC-D-ASN-OH · FMOC-D-ASN · Fmoc-D-Asparag · FMOC-D-ASPARAGINE · Nα-Fmoc-D-asparagine · N-α-Fmoc-D-asparagine · Nα-Fmoc-D-asparagine99% · N-ALPHA-FMOC-D-ASPARAGINE
Identifikatoren & physikalische Daten
| CAS No. | 108321-39-7 |
|---|---|
| Summenformel | C19H18N2O5 |
| Durchschnittliche Molmasse | 354,4 g/mol |
| Monoisotopische Masse | 354,12157168 g/mol |
| SMILES | NC(=O)C[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O |
| InChIKey | YUGBZNJSGOBFOV-MRXNPFEDSA-N |
| PubChem CID | 6992524 |
| EC No. | 991-360-6 |
| DTXSID | DTXSID50426317 |
Chemische & physikalische Eigenschaften
| XLogP | 1,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 119 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 7 |
| Schwere Atome | 26 |
| Formalladung | 0 |
| Komplexität | 530 |
| Schmelzpunkt | ~185 °C (dec.) |
| Siedepunkt | 678.6±55.0 °C(Predicted) |
| Dichte | 1.362±0.06 g/cm3(Predicted) |
| Brechungsindex | 12 ° (C=1, DMF) |
| Lagerbedingungen | Sealed in dry,2-8°C |
| Löslichkeit | Soluble in water or 1% acetic acid |
| pKa (Säurekonstante) | 3.68±0.10(Predicted) |
| Aggregatzustand | powder to crystal |
| Farbe | White to Almost white |
| BRN | 8510210 |
| Hauptanwendungen | peptide synthesis |
| InChI | InChI=1S/C19H18N2O5/c20-17(22)9-16(18(23)24)21-19(25)26-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15-16H,9-10H2,(H2,20,22)(H,21,25)(H,23,24)/t16-/m1/s1 |
| InChIKey | YUGBZNJSGOBFOV-MRXNPFEDSA-N |
| SMILES | C(O)(=O)[C@@H](CC(N)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O |
| CAS Datenbank | 108321-39-7(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29242100 |
| Sicherheitshinweise (S) | 24/25 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Nα-Fmoc-D-asparagine is an N-Fmoc-protected form of D-Asparagine (A788990). D-Asparagine is an isomer of L-Asparagine (A790005) and is used by bacteria (such as Saccharomyces cerevisiae) as a sole nitrogen source for replication. L-Asparagine is also a competitive inhibitor of staphylococcal L-asparaginase and is used as a reagent to synthesize peptide antibiotics.