HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(2R,3S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-hydroxybutanoic acid
n-[(9h-fluoren-9-ylmethoxy)carbonyl]-d-threonine · n-fmoc-d-threonine · FMOC-D-THR-OH USP/EP/BP · FMOC-D-THREONINE extrapure · N-Fmoc-D-threonine Fmoc-D-Thr-OH · N-(9-Fluorenylmethoxycarbonyl)-D-threonine · N-α-(9-Fluorenylmethoxycarbonyl)-D-threonine · (((9H-Fluoren-9-yl)methoxy)carbonyl)-D-threonine
Identifikatoren & physikalische Daten
| CAS No. | 157355-81-2 |
|---|---|
| Summenformel | C19H19NO5 |
| Durchschnittliche Molmasse | 341,4 g/mol |
| Monoisotopische Masse | 341,12632271 g/mol |
| SMILES | C[C@H](O)[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O |
| InChIKey | OYULCCKKLJPNPU-APPDUMDISA-N |
| PubChem CID | 6992532 |
| EC No. | 857-384-5 |
| DTXSID | DTXSID10426318 |
Chemische & physikalische Eigenschaften
| XLogP | 2,4 |
|---|---|
| Polarare Oberfläche (TPSA) | 95,9 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 5 |
| Frei drehbare Bindungen | 6 |
| Schwere Atome | 25 |
| Formalladung | 0 |
| Komplexität | 474 |
| Siedepunkt | 596.5±50.0 °C(Predicted) |
| Dichte | 1.327±0.06 g/cm3(Predicted) |
| Brechungsindex | 15 ° (C=1, DMF) |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | soluble in Methanol |
| Aggregatzustand | powder to crystal |
| pKa (Säurekonstante) | 3.49±0.10(Predicted) |
| Farbe | White to Almost white |
| Hauptanwendungen | peptide synthesis |
| InChI | 1S/C19H19NO5/c1-11(21)17(18(22)23)20-19(24)25-10-16-14-8-4-2-6-12(14)13-7-3-5-9-15(13)16/h2-9,11,16-17,21H,10H2,1H3,(H,20,24)(H,22,23)/t11-,17+/m0/s1 |
| InChIKey | OYULCCKKLJPNPU-APPDUMDISA-N |
| SMILES | N([C@H]([C@@H](O)C)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3 |
| CAS Datenbank | 157355-81-2 |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | WGK 2 |
| Zollcode | 29225090 |
| Sicherheitshinweise (S) | 24/25 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
N-Fmoc-D-threonine is an N-Fmoc-protected form of D-Threonine (T405525). D-Threonine is the unnatural isomer of L-Threonine (T405500) and is known to inhibit growth and cell wall synthesis of Mycobacterium smegmatis. D-Threonine is also used as a synthetic intermediate for the production of chiral antibiotics.