HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
D-(-)-α-Phenylglycin
D-PHENYLGLYCINE · (R)-2-AMino-2-phenylacetic acid · H-D-PHG-OH · D-ALPHA-PHENYLGLYCINE · D-(-)-PHENYLGLYCINE · (2R)-2-amino-2-phenylacetic acid · D(-)-ALPHA-PHENYLGLYCINE · ycine
Identifikatoren & physikalische Daten
| CAS No. | 875-74-1 |
|---|---|
| Summenformel | C8H9NO2 |
| Durchschnittliche Molmasse | 151,16 g/mol |
| Monoisotopische Masse | 151,06332853 g/mol |
| SMILES | N[C@@H](C(=O)O)c1ccccc1 |
| InChIKey | ZGUNAGUHMKGQNY-SSDOTTSWSA-N |
| PubChem CID | 70134 |
| ChEMBL | CHEMBL1403 |
| ChEBI | CHEBI:44962 |
| EC No. | 212-876-3 |
| DTXSID | DTXSID50889362 |
| Lokaler Name | D-(-)-α-Phenylglycin |
Chemische & physikalische Eigenschaften
| XLogP | -1,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 63,3 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 11 |
| Formalladung | 0 |
| Komplexität | 141 |
| Schmelzpunkt | 302 °C (dec.)(lit.) |
| Siedepunkt | 273.17°C (rough estimate) |
| Dichte | 1.2 g/cm3 (20℃) |
| Dampfdruck | 0Pa at 25℃ |
| Brechungsindex | -158 ° (C=1, 1mol/L HCl) |
| Flammpunkt | 150 °C |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Room temperature |
| Löslichkeit | Aqueous Acid (Sparingly), Water (Slightly, Heated)0.3g/100mL |
| pKa (Säurekonstante) | 1.94±0.10(Predicted) |
| Aggregatzustand | Crystalline Powder |
| Farbe | White |
| Merck | 14,7291 |
| BRN | 2208676 |
| Hauptanwendungen | detection |
| InChI | 1S/C8H9NO2/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7H,9H2,(H,10,11)/t7-/m1/s1 |
| InChIKey | ZGUNAGUHMKGQNY-SSDOTTSWSA-N |
| SMILES | N[C@@H](C(O)=O)c1ccccc1 |
| LogP (Verteilungskoeffizient) | -1.76 at 20℃ |
| CAS Datenbank | 875-74-1(CAS DataBase Reference) |
| NIST chemische Informationen | d a-Phenylglycine(875-74-1) |
| EPA chemische Informationen | Benzeneacetic acid, .alpha.-amino-, (.alpha.R)- (875-74-1) |
Sicherheit & Vorschriften
| GHS-Einstufung | This chemical does not meet GHS hazard criteria for 50% (2 of 4) of reports.WarningH315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Benzeneacetic acid, .alpha.-amino-, (R)-Status: Active Update: 03-04-2014 https://echa.europa.eu/registration-dossier/-/registered-dossier/5244Benzeneacetic acid, .alpha.-amino-, (.alpha.R)-: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Skin Irrit. 2 (50%) |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29224995 |
| R-Sätze (R) | 23/24/25-36/37/38-22-20 |
| Gefahrensymbole | T |
| Sicherheitshinweise (S) | 22-24/25-45-36/37/39-26-44-28-7-4 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
D-(-)-2-Phenylglycine is the derivative of glycine (G615990), a non-essential amino acid for human development. Glycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA r eceptors.