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HCID 7019Erstellt: 4. November 2026

Aminoacridin

AMINACRINE · Aminoacridine · Aminacrin · Acridin-9-amine · 9AA · 9-acridinamine · Acramine · Acriflex

https://huagongshe.com/de/chemical/7019

Molekülstruktur von Aminoacridin

Identifikatoren & physikalische Daten

CAS No.90-45-9
SummenformelC13H10N2
Durchschnittliche Molmasse194,23 g/mol
Monoisotopische Masse194,08439833 g/mol
SMILESNc1c2ccccc2nc2ccccc12
InChIKeyXJGFWWJLMVZSIG-UHFFFAOYSA-N
PubChem CID7019
ChEMBLCHEMBL43184
ChEBICHEBI:74789
EC No.201-995-6
DTXSIDDTXSID2024456
Lokaler NameAminoacridin

Chemische & physikalische Eigenschaften

XLogP2,8
Polarare Oberfläche (TPSA)38,9
H-Brücken-Donoren1
H-Brücken-Akzeptoren2
Frei drehbare Bindungen0
Schwere Atome15
Formalladung0
Komplexität207
Löslichkeitless than 1 mg/mL at 68 °F (NTP, 1992)ethanol: hazy11.65mg/L(24 ºC)
Schmelzpunkt466 °F (NTP, 1992)238-240℃
Physical Description9-aminoacridine appears as yellow needles. Free soluble in alcohol.
Kovats Retention Index2240
Collision Cross Section139.3 Ų [M-H]- [CCS Type: DTBuffer gas: N2Ionization: ESI-Dataset: TOXCASTSource Identifier: DTXSID7024457]138.9 Ų [M+H]+ [CCS Type: DTIonization: ESI+139.0 Ų [M]+ [CCS Type: DTIonization: APCI+138.8 Ų [M+H]+ [CCS Type: DT136.8 Ų [M+H]+ [CCS Type: TWMethod: calibrated with polyalanine and drug standards]147.66 Ų [M+K]+ [CCS Type: TW131.39 Ų [M+H-H2O]+ [CCS Type: TW135 Ų [M+H]+ [CCS Type: TW
Siedepunkt320.68°C (rough estimate)
Dichte1.268
Brechungsindex1.5014 (estimate)
LagerbedingungenStore below +30°C.
pKa (Säurekonstante)9.99(at 20℃)
AggregatzustandSolid
FarbeYellow
Merck14,407
StabilitätStable. Incompatible with strong oxidizing agents.
InChI1S/C13H10N2/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13/h1-8H,(H2,14,15)
InChIKeyXJGFWWJLMVZSIG-UHFFFAOYSA-N
SMILESNc1c2ccccc2nc3ccccc13
CAS Datenbank90-45-9(CAS DataBase Reference)
EPA chemische Informationen9-Aminoacridine (90-45-9)

Sicherheit & Vorschriften

GHS-EinstufungWarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (97.5%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Regulatorische InformationenChemical: 9-Acridinamine9-Aminoacridine: Does not have an individual approval but may be used under an appropriate group standard
Weitere SicherheitsinformationenEvaluation - Chemicals not considered for in depth evaluation - Not commercially active in Australia
BrandgefahrenFlash point data for this chemical are not availablehowever, it is probably combustible. (NTP, 1992)
GesundheitsgefahrenSYMPTOMS: Symptoms of exposure to this compound may include gastrointestinal mucosa irritation, nausea and vomiting.ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes of NOx. (NTP, 1992)
Reaktive GruppeAmines, Phosphines, and PyridinesHydrocarbons, Aromatic
Reactivity Profile9-AMINOACRIDINE is a moderately strong base. Neutralizes acids to form salts plus water in exothermic reactions. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Anwendungen & Verwendung

Verwenden

Acridine analog. DNA intercalating agent.

Air and Water ReactionsInsoluble in water.
Hazard Classes and CategoriesSkin Irrit. 2 (100%)Eye Irrit. 2 (100%)STOT SE 3 (97.5%)
BrandbekämpfungFires involving this material can be controlled using a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
Erste HilfeEYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.SKIN: IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.INHALATION: IMMEDIATELY leave the contaminated areatake deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be usedif not available, use a level of protection greater than or equal to that advised under Protective Clothing.INGESTION: If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Generally, the induction of vomiting is NOT recommended outside of a physician's care due to the risk of aspirating the chemical into the victim's lungs. However, if the victim is conscious and not convulsing and if medical help is not readily available, consider the risk of inducing vomiting because of the high toxicity of the chemical ingested. Ipecac syrup or salt water may be used in such an emergency. IMMEDIATELY transport the victim to a hospital. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital. (NTP, 1992)
Freisetung ohne BrandSMALL SPILLS AND LEAKAGE: Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.STORAGE PRECAUTIONS: You should store this material under ambient temperatures. (NTP, 1992)
Personal Protective Equipment (PPE)RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter). (NTP, 1992)
Wassergefährdungsklasse (WGK)3
UN-Transportnummer2811
Zollcode2933 99 80
RTECS-Nr.AR7300000
R-Sätze (R)36/37/38
ToxizitätLD50 intraperitoneal in mouse: 68mg/kg
GefahrensymboleXi
Sicherheitshinweise (S)26-36
Gefahrenklasse6.1(b)Acute Tox. 4 OralAquatic Acute 1Aquatic Chronic 1Eye Irrit. 2Skin Irrit. 2STOT SE 3
VerpackungsgruppeIII
Lagerklasse11 - Combustible Solids