HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-Methylmaleimid
1-METHYL-1H-PYRROLE-2,5-DIONE · N-METHYLMALEIMID · N-Methylmaleinimide · N-Methyl-Malemide · N-METHYLMALEIMIDE · Maleimide,N-methyl- · Maleimide, N-methyl- · N-Methylmaleimide>N-Methylmaleimide,97%
Identifikatoren & physikalische Daten
| CAS No. | 930-88-1 |
|---|---|
| Summenformel | C5H5NO2 |
| Durchschnittliche Molmasse | 111,1 g/mol |
| Monoisotopische Masse | 111,0320284 g/mol |
| SMILES | CN1C(=O)C=CC1=O |
| InChIKey | SEEYREPSKCQBBF-UHFFFAOYSA-N |
| PubChem CID | 70261 |
| ChEMBL | CHEMBL225037 |
| ChEBI | CHEBI:232160 |
| EC No. | 213-226-1 |
| DTXSID | DTXSID30239240 |
| Lokaler Name | N-Methylmaleimid |
Chemische & physikalische Eigenschaften
| XLogP | -0,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 37,4 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 153 |
| Kovats Retention Index | 925.1 |
| Schmelzpunkt | 94-96 °C (lit.) |
| Siedepunkt | 208.19°C (rough estimate) |
| Dichte | 1.3113 (rough estimate) |
| Brechungsindex | 1.4260 (estimate) |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Room Temperature |
| Löslichkeit | Chloroform (Sparingly), Methanol (Slightly)Slightly soluble in water. |
| pKa (Säurekonstante) | -2.18±0.20(Predicted) |
| Aggregatzustand | Crystals |
| Farbe | Light yellow |
| BRN | 108550 |
| InChI | InChI=1S/C5H5NO2/c1-6-4(7)2-3-5(6)8/h2-3H,1H3 |
| InChIKey | SEEYREPSKCQBBF-UHFFFAOYSA-N |
| SMILES | N1(C)C(=O)C=CC1=O |
| CAS Datenbank | 930-88-1(CAS DataBase Reference) |
| NIST chemische Informationen | N-Methylmaleimide(930-88-1) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH302 (92.5%): Harmful if swallowed [Warning Acute toxicity, oral]H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]P260, P261, P264, P270, P272, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P354+P338, P316, P321, P330, P333+P317, P362+P364, P363, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 53 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Acute Tox. 4 (92.5%)Skin Corr. 1C (100%)Skin Sens. 1 (100%) |
| F | 10-21 |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | UN 1759 8/PG 2 |
| Zollcode | 29241990 |
| RTECS-Nr. | ON5600000 |
| R-Sätze (R) | 22-34-43-25-20/21 |
| Gefahrensymbole | C |
| Sicherheitshinweise (S) | 26-36/37/39-45 |
| Gefahrenklasse | 6.1Acute Tox. 4 OralSkin Corr. 1BSkin Sens. 1 |
| Verpackungsgruppe | II |
| Lagerklasse | 8A - Combustible corrosive hazardous materials |
Anwendungen & Verwendung
Verwenden
N-Methylmaleimide is an electron deficient olefin that acts as a thiol-blocking reagent.