N-Acetyltryptamine
Acetotryptamide · N-ACETYLTRYPTAMINE · Nb-Acetyltryptamine · N-(2-(1H-Indol-3-yl) · N10-Acetyltryptamine · Acetyltryptamine, N- · TRYPTAMINE, N-ACETYL- · N-Acetyltryptamine >N-Acetyltryptamine
Identifikatoren & physikalische Daten
| CAS No. | 1016-47-3 |
|---|---|
| Summenformel | C12H14N2O |
| Durchschnittliche Molmasse | 202,25 g/mol |
| Monoisotopische Masse | 202,11061307 g/mol |
| SMILES | CC(=O)NCCc1c[nH]c2ccccc12 |
| InChIKey | NVUGEQAEQJTCIX-UHFFFAOYSA-N |
| PubChem CID | 70547 |
| ChEMBL | CHEMBL33171 |
| ChEBI | CHEBI:55515 |
| DTXSID | DTXSID30144042 |
Chemische & physikalische Eigenschaften
| XLogP | 1,8 |
|---|---|
| Polarare Oberfläche (TPSA) | 44,9 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 3 |
| Schwere Atome | 15 |
| Formalladung | 0 |
| Komplexität | 230 |
| SpringerMaterials Properties | Chemical shift |
| LogP (Verteilungskoeffizient) | 1.41 |
| Schmelzpunkt | 74.0 to 78.0 °C |
| Siedepunkt | 200°C/0.2mmHg(lit.) |
| Dichte | 1.164±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Sealed in dry,Room Temperature |
| Löslichkeit | alcohol: soluble |
| Aggregatzustand | powder |
| pKa (Säurekonstante) | 16.48±0.46(Predicted) |
| Farbe | White to Light yellow to Light orange |
| CAS Datenbank | 1016-47-3 |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| Zollcode | 2933.99.8290 |
| Sicherheitshinweise (S) | 22-24/25 |
Anwendungen & Verwendung
Beschreibung
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.
Verwenden
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.