HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N-Acetyl-3,5-diiod-L-tyrosin
N-Acetyl-3, · Ac-Tyr(3,5-DiI)-OH · 5-Diiodo-L-Tyrosine · AC-3,5-DIIODO-TYR-OH · Levothyroxine Impurity 66 · N-Acetyl-3,5-diiodotyrosine · N-Acetyl-3,5-diiod-L-tyrosin · 3,5-DIIODO-N-ACETYL-L-TYROSINE
Identifikatoren & physikalische Daten
| CAS No. | 1027-28-7 |
|---|---|
| Summenformel | C11H11I2NO4 |
| Durchschnittliche Molmasse | 475,02 g/mol |
| Monoisotopische Masse | 474,87775 g/mol |
| SMILES | CC(=O)NC(Cc1cc(I)c(O)c(I)c1)C(=O)O |
| InChIKey | CDXURJOCZAIXFK-UHFFFAOYSA-N |
| PubChem CID | 70565 |
| EC No. | 213-837-3 |
| Lokaler Name | N-Acetyl-3,5-diiod-L-tyrosin |
Chemische & physikalische Eigenschaften
| XLogP | 2,1 |
|---|---|
| Polarare Oberfläche (TPSA) | 86,6 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 4 |
| Schwere Atome | 18 |
| Formalladung | 0 |
| Komplexität | 314 |
| Schmelzpunkt | 124.0 to 128.0 °C |
| Siedepunkt | 532.9±50.0 °C(Predicted) |
| Dichte | 2.206±0.06 g/cm3(Predicted) |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| Löslichkeit | almost transparency in Methanol |
| Aggregatzustand | powder to crystal |
| pKa (Säurekonstante) | 2.98±0.10(Predicted) |
| Farbe | White to Light yellow to Light orange |
| CAS Datenbank | 1027-28-7(CAS DataBase Reference) |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| Zollcode | 2922.49.4950 |
| Sicherheitshinweise (S) | 22-24/25 |
Anwendungen & Verwendung
Verwenden
N-Acetyl-3,5-diiodo-L-tyrosine has been used in the modeling system to study thyroid hormone biosynthesis. N-Acetyl-3,5-diiodo-L-tyrosine was also investigated for its ability to inhibit pepsin-cata lyzed hydrolysis to determine the substrate binding region of the active center of the enzyme.