HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
2-Chlor-2',6'-dimethylacetanilid
Lidocaine EP Impurity H · 2-CHLORO-2',6'-ACETOXYLIDIDE · N-CHLOROACETYL-2,6-DIMETHYLANILINE · NSC 37260 · 2-Chloro-N-(2 · acetoxylidide · AKOS BBS-00000875 · LIDOCAINE EP IMP H
Identifikatoren & physikalische Daten
| CAS No. | 1131-01-7 |
|---|---|
| Summenformel | C10H12ClNO |
| Durchschnittliche Molmasse | 197,66 g/mol |
| Monoisotopische Masse | 197,0607417 g/mol |
| SMILES | Cc1cccc(C)c1NC(=O)CCl |
| InChIKey | FPQQSNUTBWFFLB-UHFFFAOYSA-N |
| PubChem CID | 70798 |
| EC No. | 214-460-7 |
| DTXSID | DTXSID4061545 |
| Lokaler Name | 2-Chlor-2',6'-dimethylacetanilid |
Chemische & physikalische Eigenschaften
| XLogP | 1,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 29,1 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 2 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 174 |
| Physical Description | White or grey powder[Alfa Aesar MSDS] |
| Schmelzpunkt | 150-151 °C(lit.) |
| Siedepunkt | 316.8±30.0 °C(Predicted) |
| Dichte | 1.1363 (rough estimate) |
| Brechungsindex | 1.5330 (estimate) |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)Soluble in Chloroform, Methanol. Insoluble in water. |
| pKa (Säurekonstante) | 12.91±0.70(Predicted) |
| Aggregatzustand | Crystalline Powder or Needles |
| Farbe | White to brown |
| BRN | 781309 |
| Stabilität | Light Sensitive |
| InChI | 1S/C10H12ClNO/c1-7-4-3-5-8(2)10(7)12-9(13)6-11/h3-5H,6H2,1-2H3,(H,12,13) |
| InChIKey | FPQQSNUTBWFFLB-UHFFFAOYSA-N |
| SMILES | Cc1cccc(C)c1NC(=O)CCl |
| CAS Datenbank | 1131-01-7(CAS DataBase Reference) |
| NIST chemische Informationen | 2-Chloro-2',6'-acetoxylidide(1131-01-7) |
| EPA chemische Informationen | Acetamide, 2-chloro-N-(2,6-dimethylphenyl)- (1131-01-7) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (70.3%): Harmful if swallowed [Warning Acute toxicity, oral]H315 (29.7%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (99.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (29.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 165 reports by companies from 11 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Regulatorische Informationen | Status: Active Update: 29-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/18637 |
| Gefahrenübersicht | A skin and strong eye irritant[Alfa Aesar MSDS] See Acetanilide. |
| Hazard Classes and Categories | Acute Tox. 4 (70.3%)Skin Irrit. 2 (29.7%)Eye Irrit. 2 (99.4%)STOT SE 3 (29.1%) |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29214200 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26-37/39 |
| Gefahrenklasse | IRRITANTEye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Lidocaine intermediate.