Grundinformationen
- CAS
92-32-0- Standard-SMILES
CN(C)c1ccc2cc3ccc(=[N+](C)C)cc-3oc2c1.[Cl-]- InChIKey
INCIMLINXXICKS-UHFFFAOYSA-M- Summenformel
- C17H19N2O.Cl
- Durchschnittliche Molmasse
- 302,8 g/mol
- Monoisotopische Masse
- 302,1185909
Überblick
Pyronin Y is an organic chloride salt having 6-(dimethylamino)-N,N-dimethyl-3H-xanthen-3-iminium as the cation. Used with methyl green to selectively demonstrate RNA (red) in contrast to DNA (green) with the Unna-Pappenheim method. It has a role as a histological dye. It is an iminium salt and an organic chloride salt. It contains a pyronin Y cation.
Namen und Bezeichner
- Bevorzugter Name
- Pyronine
- IUPAC
- [6-(dimethylamino)xanthen-3-ylidene]-dimethylazanium chloride
- Lokaler Name
- 3,6-Bis(dimethylamino)xanthyliumchlorid
- Englischer Name
- PYRONIN Y
- Summenformel
- C17H19ClN2O
- Molmasse
- 302.8
Namen und Synonyme
Pyronin Y92-32-0Pyronine YPyroninePyronin GPyronin YellowPyronine GTetramethyl pyronin3,6-Bis(dimethylamino)xanthylium chlorideMethyl pyroninXanthylium, 3,6-bis(dimethylamino)-, chloridePyronine ZH
Weitere Namen anzeigen
Pyonin GPyonin YCI 45005PYRONIN J
C.I. 45005tetramethyldiaminoxanthylium chlorideSchultz No. 853NSC-10454W659G165T1CHEBI:8682DTXSID8059051CI-45005
Datenbank-Bezeichner
- CAS
92-32-0- PubChem CID
- 7085
- DTXSID
DTXSID8059051- ChEMBL
CHEMBL1486690- ChEBI
CHEBI:8682- UNII
- W659G165T1
- EC Number
- 202-147-8
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 15,5 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 21
- Formalladung
- 0
- Komplexität
- 480
Experimentelle und physikochemische Eigenschaften
Chemical ClassesDyes -> Acridine Dyes
Physical Description
Liquid
Lustrous green solid; [Merck Index] Iridescent green crystals; [Amresco MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 250 · 250-260 °C(lit.)
- storage temp.
- room temp
- Löslichkeit
- Soluble in water; sparingly soluble in ethanol, ethylene glycol, methyl cellosolve
- Aggregatzustand
- Powder/Solid
- Farbe
- Pink
- Wasserlöslichkeit
- Soluble in water. Also soluble in methyl cellosolve (9 mg/mL) and ethanol (3 mg/mL).
- Merck
- 13 · 13,8097
- BRN
- 3795789 · 3795789
- Stabilität
- Stable. Incompatible with strong oxidizing agents.
- Major Application
- diagnostic assay manufacturinghematologyhistology
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H341 (100%): Suspected of causing genetic defects [Warning Germ cell mutagenicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory Information
Chemical: Methanaminium, N-[6-(dimethylamino)-3H-xanthen-3-ylidene]-N-methyl-, chloride
Xanthylium, 3,6-bis(dimethylamino)-, chloride (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Xanthylium, 3,6-bis(dimethylamino)-, chloride (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
Xanthylium, 3,6-bis(dimethylamino)-, chloride: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryCauses changes in kidneys (acute tubular necrosis) in intravenous lethal-dose studies of mice (LD50 = 179 mg/kg); [RTECS] A skin and strong eye irritant; Targets the kidney and bladder; [Amresco MSDS]
Hazard Classes and CategoriesMuta. 2 (100%)
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 32041300
- RTECS-Nr.
- BQ1450000
- risk_code
- 68-36/37/38
- hazard_code
- Xn,Xi
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationChemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
Verwendung und Herstellung
UsesUsed as a bacterial and biological stain; [Merck Index]
U.S. Production2022: 11,116 lb
Industry UsesFiller
General Manufacturing Information
All Other Chemical Product and Preparation Manufacturing
Xanthylium, 3,6-bis(dimethylamino)-, chloride (1:1): ACTIVE
Anwendungen
VerwendenPyronin Y is a cationic dye that intercalates RNA and is visible as a red band during electrophoresis. It has also been shown to accumulate in mitochondria of viable cells. In conjuction with Methyl Green or Nancy-520, Pyronin Y can be used as a fluorescent differential stain of nucleic acids in paraffin tissue sections.
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